Art

J-GLOBAL ID：201002212248295821   Reference number：10A1043355

Molecular Mechanisms of Ezetimibe-Induced Attenuation of Postprandial Hypertriglyceridemia

エゼチミブによる食後高トリグリセリド血症の抑制機序

Author (16)： SANDOVAL Jose C. (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.) ,  NAKAGAWA-TOYAMA Yumiko (Health Care Center, Osaka Univ.) ,  MASUDA Daisaku (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.) ,  TOCHINO Yoshihiro (Dep. of Metabolic Medicine, Osaka Univ. Graduate School of Medicine.) ,  NAKAOKA Hajime (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.) ,  KAWASE Ryota (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.) ,  YUASA-KAWASE Miyako (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.) ,  NAKATANI Kazuhiro (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.) ,  INAGAKI Miwako (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.) ,  TSUBAKIO-YAMAMOTO Kazumi (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.) ,  OHAMA Tohru (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.) ,  MATSUYAMA Akifumi (Lab. for Somatic Stem Cell Therapy, Foundation of Biomedical Res. and Innovation.) ,  NISHIDA Makoto (Health Care Center, Osaka Univ.) ,  ISHIGAMI Masato (Dep. of Biomedical Informatics, Div. of Health Sciences, Osaka Univ. Graduate School of Medicine.) ,  KOMURO Issei (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.) ,  YAMASHITA Shizuya (Dep. of Cardiovascular Medicine, Osaka Univ. Graduate School of Medicine.)
Material： Journal of Atherosclerosis and Thrombosis (Web)  (J Atheroscler Thromb (Web))
Volume： 17  Issue： 9  Page： 914-924 (J-STAGE)  Publication year： 2010 
JST Material Number： U0153A  ISSN： 1880-3873  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： CD36 ,...

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JST classification (2)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Basic research of drugs acting on lipid metabolism  (GW13040M)

Substance index (1)： Ezetimibe

Reference (31)：

• 1)Third Report of the National Cholesterol Education Pro-gram (NCEP): Expert Panel on Detection, Evaluation and Treatment of High Blood cholesterol in Adults (Adult treatment panel III). Final Report. Circulation, 2002; 106: 3163-3223
• 2)Nordestgaard B, Benn M, Schnohr P, Tybjærg-Hansen A: Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA, 2007; 298: 299-308
• 3)Freiberg JJ, Tybjaerg-Hansen A, Jensen JS, Nordestgaard BG: Nonfasting triglycerides and risk of ischemic stroke in the general population. JAMA, 2008; 300: 2142-2152
• 4)Huff MW: Dietary cholesterol, cholesterol absorption, postprandial lipemia and aterosclerosis. Can J Clin Phar-macol, 2003; 10 (Suppl A): 26A-32A
• 5)Zilversmit DB: Atherogenesis: A postprandial phenome-non. Circulation, 1979; 60: 473-485

Terms in the title (2)： エゼチミブ ,  食後高トリグリセリド血症