Art

J-GLOBAL ID：201002212871913234   Reference number：10A0335909

Protein disulfide isomerase-P5, down-regulated in the final stage of boar epididymal sperm maturation, catalyzes disulfide formation to inhibit protein function in oxidative refolding of reduced denatured lysozyme

イノシシの精巣上体精子成熟の最終段階においてダウンレギュレートされる蛋白質ジスルフィドイソメラーゼP5は,ジスルフィド形成を触媒して還元変性リゾチームの酸化的再折畳みの蛋白質機能を阻害する

Author (21)： AKAMA Kuniko (Graduate School of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  AKAMA Kuniko (Graduate School of Sci. and Technol., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  HORIKOSHI Tomoe (Graduate School of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  SUGIYAMA Atsushi (Graduate School of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  NAKAHATA Satoko (Graduate School of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  AKITSU Aoi (Dep. of Chemistry, Fac. of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  NIWA Nobuyoshi (Dep. of Chemistry, Fac. of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  INTOH Atsushi (Dep. of Chemistry, Fac. of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  KAKUI Yasutaka (Dep. of Chemistry, Fac. of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  SUGAYA Michiko (Graduate School of Sci. and Technol., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  TAKEI Kazuo (Dep. of Chemistry, Fac. of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  IMAIZUMI Noriaki (Dep. of Chemistry, Fac. of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  SATO Takaya (Dep. of Chemistry, Fac. of Sci., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  MATSUMOTO Rena (Graduate School of Sci. and Technol., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  MATSUMOTO Rena (International Patent Organism Depositary, National Inst. of Advanced Industrial Sci. and Technol., Central 6, 1-1-1 ...) ,  IWAHASHI Hitoshi (Graduate School of Sci. and Technol., Chiba Univ., 1-33 Yayoi-Cho, Inage-Ku, Chiba 263-8522, JPN) ,  IWAHASHI Hitoshi (International Patent Organism Depositary, National Inst. of Advanced Industrial Sci. and Technol., Central 6, 1-1-1 ...) ,  KASHIWABARA Shin-ichi (Graduate School of Life and Environmental Sciences, Univ. of Tsukuba, Tsukuba Sci. City, Ibaraki 305-8572, JPN) ,  BABA Tadashi (Graduate School of Life and Environmental Sciences, Univ. of Tsukuba, Tsukuba Sci. City, Ibaraki 305-8572, JPN) ,  NAKAMURA Megumi (Res. Team for Molecular Biomarkers, Tokyo Metropolitan Inst. of Gerontology, Tokyo 173-0015, JPN) ,  TODA Tosifusa (Res. Team for Molecular Biomarkers, Tokyo Metropolitan Inst. of Gerontology, Tokyo 173-0015, JPN)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1804  Issue： 6  Page： 1272-1284  Publication year： Jun. 2010 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Sus ,  *epididymis ,  Spermatogenesis ,  *protein disulfide-isomerase ,  Down-Regulation ,  cDNA ,  recombinant protein ,  Escherichia coli ,  enzyme activity ,  folded structure ,  disulfide bond ,  crosslinking ,  fertility (reproduction) ,  lysozyme ,  sulfur oxidoreductase ,  Sus scrofa domesticus ,  spermatozoon ,  nucleotide sequence ,  Amino Acid Sequence ,  amino acid residue ,  homology (characteristic) ,  Sperm Maturation ,  protein disulfide reductase ,  differentiation (biology) ,  developmental physiology ,  microorganism ,  Artiodactyla
Semi thesaurus term： 蛋白質ジスルフィドイソメラーゼA3 ,  *蛋白質ジスルフィドイソメラーゼP5

JST classification (2)： Enzyme in general  (EB09010D) ,  Reproductive(=genital)organs  (EJ15020P)

Terms in the title (14)： イノシシ ,  精巣上体 ,  精子成熟 ,  段階 ,  蛋白質ジスルフィドイソメラーゼ ,  ジスルフィド ,  触媒 ,  還元 ,  変性 ,  リゾチーム ,  酸化 ,  折畳み ,  蛋白質機能 ,  阻害