Art

J-GLOBAL ID：201002216761924600   Reference number：10A0222204

Inhibitory effects of soluble MD-2 and soluble CD14 on bacterial growth

細菌増殖に対する可溶性MD-2及び可溶性CD14の阻害作用

Author (3)： OHNISHI Takahiro (National Inst. Health Sci., Tokyo) ,  MUROI Masashi (Musashino Univ., Tokyo, JPN) ,  TANAMOTO Ken-ichi (Musashino Univ., Tokyo, JPN)
Material： Microbiology and Immunology  (Microbiol Immunol)
Volume： 54  Issue： 2  Page： 74-80  Publication year： Feb. 2010 
JST Material Number： W1957A  ISSN： 0385-5600  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *Proteins ,...
Semi thesaurus term： endotoxin

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=10A0222204&from=J-GLOBAL&jstjournalNo=W1957A") }}

JST classification (2)： Infectious immunity  (ED03030P) ,  Differentiation,propagation,growth,reproduction  (EG03055B)

Reference (28)：

• VISINTIN, A. Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4. Proc Natl Acad Sci USA. 2001, 98, 12156-12161
• SCHROMM, A. B. Molecular genetic analysis of an endotoxin nonresponder mutant cell line : a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. J Exp Med. 2001, 194, 79-88
• NAGAI, Y. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat Immunol. 2002, 3, 667-672
• OHNISHI, T. MD-2 is necessary for the toll-like receptor 4 protein to undergo glycosylation essential for its translocation to the cell surface. Clin Diagn Lab Immunol. 2003, 10, 405-410
• MUROI, M. Regions of the mouse CD14 molecule required for toll-like receptor 2- and 4-mediated activation of NF-kappa B. J Biol Chem. 2002, 277, 42372-42379

Terms in the title (5)： 細菌増殖 ,  可溶性 ,  MD-2 ,  CD14 ,  阻害作用