Art

J-GLOBAL ID：201002228017185253   Reference number：10A0770530

Effect of Additives on Polymorphic Transition of Theophylline in Mechano-Chemical Processing

メカノ化学プロセスにおけるテオフィリンの多形転移に及ぼす添加剤の影響

Author (2)： KISHI Yoshifumi (Dep. of Chemical Engineering, Tokyo Univ. of Agriculture and Technol.) ,  MATSUOKA Masakuni (Dep. of Chemical Engineering, Tokyo Univ. of Agriculture and Technol.)
Material： Journal of Chemical Engineering of Japan  (J Chem Eng Jpn)
Volume： 43  Issue： 7  Page： 553-560 (J-STAGE)  Publication year： 2010 
JST Material Number： S0629A  ISSN： 0021-9592  CODEN： JCEJAQ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *urea compound ,  *lactam ,  *solid phase reaction ,  *polymorphic transition ,  *additive ,  polymorphism ,  crystal morphology ,  energy ,  nitrogen heterocyclic compound ,  hydroxy compound ,  central nervous system stimulant
Semi thesaurus term： Purines ,  *mechanochemical reaction ,  機械的エネルギー

JST classification (2)： Crystal structure of heterocyclic compounds  (BK08030Q) ,  Experimental operation and apparatus of basic chemistry  (CA02000Q)

Substance index (5)： Caffeine ,  Theophylline ,  Theobromine ,  Paraxanthine ,  Uric Acid

Reference (31)：

• Airaksinen, S., M. Karjalainen, E. Räsänen, J. Rantanen and J. Yliruusi; “Comparison of The Effects of Two Drying Methods on Polymorphism of Theophylline,” Int. J. Pharm., 276, 129–141 (2004)
• Bernstein, J.; Polymorphism in Molecular Crystals, p. 126, Oxford University Press, Oxford, UK (2002)
• Cashell, C., D. Corcoran and B. K. Hodnett; “Control of Polymorphism and Crystal Size of L-glutamic Acid in The Absence of Additives,” J. Cryst. Growth, 273, 258–265 (2004)
• Datta, S. and D. J. W. Grant; “Crystal Structures of Drugs: Advances in Determination, Prediction and Engineering,” Nat. Rev. Drug Discovery, 3, 42–57 (2004)
• Edwards, H. G. M., E. Lawson, M. Matas, L. Shields and P. York; “Metamorphosis of Caffeine Hydrate and Anhydrous Caffeine,” J. Chem. Soc. Perkin Trans., 2, 1985–1990 (1997)

Terms in the title (5)： メカノ化学 ,  プロセス ,  テオフィリン ,  多形転移 ,  添加剤