Art

J-GLOBAL ID：201002229616139363   Reference number：10A0770815

Endothelin Type B Receptor-Induced Sustained Ca²⁺ Influx Involves G_q/11/Phospholipase C-Independent, p38 Mitogen-Activated Protein Kinase-Dependent Activation of Na⁺/H⁺ Exchanger

エンドセリンB受容体に誘導される持続性Ca²⁺流入はG_q/11/ホスホリパーゼCに非依存的でp38マイトジェン活性化蛋白質キナーゼに依存的なNa⁺/H⁺交換輸送体活性化に関与する

Author (8)： HIGA Tsunaki (Dep. of Cellular Pharmacology, Hokkaido Univ. Graduate School of Medicine, JPN) ,  HORINOUCHI Takahiro (Dep. of Cellular Pharmacology, Hokkaido Univ. Graduate School of Medicine, JPN) ,  AOYAGI Hiroyuki (Dep. of Cellular Pharmacology, Hokkaido Univ. Graduate School of Medicine, JPN) ,  ASANO Hiroshi (Dep. of Cellular Pharmacology, Hokkaido Univ. Graduate School of Medicine, JPN) ,  NISHIYA Tadashi (Dep. of Cellular Pharmacology, Hokkaido Univ. Graduate School of Medicine, JPN) ,  NISHIMOTO Arata (Dep. of Cellular Pharmacology, Hokkaido Univ. Graduate School of Medicine, JPN) ,  MURAMATSU Ikunobu (Div. of Pharmacology, Dep. of Biochemistry and Bioinformative Sciences, School of Medicine, Univ. of Fukui, JPN) ,  MIWA Soichi (Dep. of Cellular Pharmacology, Hokkaido Univ. Graduate School of Medicine, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 113  Issue： 3  Page： 276-280 (J-STAGE)  Publication year： 2010 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： molecular genetic phenomenon ,...
Semi thesaurus term： Gq protein ,...

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JST classification (1)： Receptors on cell membrane  (EF04030C)

Reference (15)：

• BERRIDGE, MJ. Calcium signalling : dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol. 2003, 4, 517-529
• SPASSOVA, MA. Calcium entry mediated by SOCs and TRP channels : variations and enigma. Biochim Biophys Acta. 2004, 1742, 9-20
• MIWA, S. Ca^<2+> entry channels involved in endothelin-1-induced contractions of vascular smooth muscle cells. J Smooth Muscle Res. 2005, 41, 61-75
• KAWANABE, Y. Molecular mechanisms for the activation of voltage-independent Ca^<2+> channels by endothelin-1 in Chinese hamster ovary cells stably expressing human endothelin_A receptors. Mol Pharmacol. 2002, 62, 75-80
• HORINOUCHI, T. Functional role of Na^+/H^+ exchanger in Ca^<2+> influx mediated via human endothelin type A receptor stably expressed in Chinese hamster ovary cells. J Pharmacol Sci. 2008, 107, 456-459

Terms in the title (10)： エンドセリンB受容体 ,  誘導 ,  持続性 ,  Ca2+流入 ,  ホスホリパーゼC ,  非依存 ,  P38 ,  マイトジェン活性化蛋白質キナーゼ ,  輸送体 ,  活性化