Rchr
J-GLOBAL ID:200901037787170470
Update date: Jun. 06, 2020
Nishiya Tadashi
ニシヤ タダシ | Nishiya Tadashi
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Affiliation and department:
Ohu University The School of Pharmaceutical Science
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Detailed information
Job title:
Lecturer
Research field (2):
Pharmaceuticals - health and biochemistry
, Medical biochemistry
Research keywords (7):
ユビキチン化
, SPSB
, iNOS
, E3 ubiquitin ligase
, 炎症
, innate immunity
, Inflammation
Research theme for competitive and other funds (2):
2005 - S-nitrosylationを介した自然免疫反応の制御機構
2004 - 病原体の認識および細胞応答に関わる分子機構の解明
MISC (25):
Takashi Uehara, Tadashi Nishiya. Screening systems for the identification of S-nitrosylated proteins. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2011. 25. 2. 108-111
Regulation of inducible nitric oxide synthase by the SPRY domain- and SOCS box-containing proteins. Journal of Biological Chemistry. 2011. in press
Tsunaki Higa, Takahiro Horinouchi, Hiroyuki Aoyagi, Hiroshi Asano, Tadashi Nishiya, Arata Nishimoto, Ikunobu Muramatsu, Soichi Miwa. Endothelin Type B Receptor-Induced Sustained Ca2+ Influx Involves G(q/11)/Phospholipase C-Independent, p38 Mitogen-Activated Protein Kinase-Dependent Activation of Na+/H+ Exchanger. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2010. 113. 3. 276-280
Arata Nishimoto, Lingyun Lu, Misato Hayashi, Tadashi Nishiya, Takahiro Horinouchi, Soichi Miwa. Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010. 391. 4. 1616-1622
Takahiro Horinouchi, Hiroshi Asano, Tunaki Higa, Arata Nishimoto, Tadashi Nishiya, Ikunobu Muramatsu, Soichi Miwa. Differential Coupling of Human Endothelin Type A Receptor to G(q/11) and G(12) Proteins: the Functional Significance of Receptor Expression Level in Generating Multiple Receptor Signaling. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2009. 111. 4. 338-351
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Works (5):
細菌感染時にS-ニトロシル化される蛋白質の同定とその敗血症の病態形成への関与
2008 - 2010
金属アレルギーの克服へ向けた効果的診断・予防・治療法の開発研究
2007 - 2009
敗血症におけるS-ニトロシル化蛋白質の機能解析と治療への応用
2007 -
敗血症の分子機構の解明-誘導型一酸化窒素合成酵素の発現とS-ニトロシル化反応による免疫系の制御機構
2007 -
免疫応答におけるToll様受容体の局在の重要性とそれに関わる膜蛋白輸送経路の解明
2006 -
Education (8):
1996 - 1999 北大 院薬 博士
- 1999 Hokkaido University Graduate School, Division of Pharmaceutical Sciences
- 1997 Hokkaido University Graduate School, Division of Pharmaceutical Sciences
1994 - 1996 北大 院薬 修士
1991 - 1994 北大 薬 製薬化
- 1994 Hokkaido University Faculty of Pharmaceutical Science
1990 - 1991 北大 理II
1987 - 1990 弘前大 理 地球科
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Professional career (2):
博士 (薬学) (北海道大学)
薬学修士 (北海道大学)
Work history (10):
2014/04 - 現在 奥羽大 薬 教授
2011/10 - 2014/03 岡山大 薬 准教授
2006/10 - 2011/09 北大 医 講師
2005/02 - 2006/09 北大 医 助手
2005 - 2006 Research Associate
2006 - - Lecturer
2000/03 - 2005/02 UCSF ポスドク
1999/05 - 2000/02 NIH ポスドク
1997/04 - 1999/03 学振 DC2
1997 - 1999 Postdoctoral Fellowships of Japan Society for the Promotion of Science
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Association Membership(s) (4):
日本免疫学会
, 日本薬理学会
, 日本生化学会
, 日本薬学会
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