Art

J-GLOBAL ID：201002232380926602   Reference number：10A0722800

Single-Dose Intravenous Administration of Recombinant Human Erythropoietin Is a Promising Treatment for Patients With Acute Myocardial Infarction - Randomized Controlled Pilot Trial of EPO/AMI-1 Study -

組み換えヒトエリスロポイエチンの単回静脈内投与は急性心筋梗塞患者に対する有望な治療である-EPO/AMI-1研究のランダム化比較パイロット試験-

Author (12)： OZAWA Takuya (First Dep. of Internal Medicine, Niigata Univ. Medical and Dental Hospital) ,  TOBA Ken (First Dep. of Internal Medicine, Niigata Univ. Medical and Dental Hospital) ,  SUZUKI Hiroshi (Div. of Cardiology, Dep. of Internal Medicine, Showa Univ. Fujigaoka Hospital) ,  KATO Kiminori (First Dep. of Internal Medicine, Niigata Univ. Medical and Dental Hospital) ,  ISO Yoshitaka (Div. of Cardiology, Dep. of Internal Medicine, Showa Univ. Fujigaoka Hospital) ,  AKUTSU Yasushi (Div. of Cardiology, Dep. of Medicine, Showa Univ. School of Medicine) ,  KOBAYASHI Youichi (Div. of Cardiology, Dep. of Medicine, Showa Univ. School of Medicine) ,  TAKEYAMA Youichi (Div. of Cardiology, Dep. of Internal Medicine, Showa Univ. Fujigaoka Hospital) ,  KOBAYASHI Naohiko (Dep. of Hypertension and Cardiorenal Medicine, Dokkyo Univ. School of Medicine) ,  YOSHIMURA Norihiko (Div. of Radiation Oncology, Niigata Univ. Medical and Dental Hospital) ,  AKAZAWA Kohei (Div. of Medical Informatics, Niigata Univ. Medical and Dental Hospital) ,  AIZAWA Yoshifusa (First Dep. of Internal Medicine, Niigata Univ. Medical and Dental Hospital)
Material： Circulation Journal  (Circ J)
Volume： 74  Issue： 7  Page： 1415-1423 (J-STAGE)  Publication year： 2010 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *erythropoietin ,...
Semi thesaurus term： LVEF ,...

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JST classification (2)： Drug therapy(=pharmacotherapy)for cardiovascular system diseases  (GJ05020M) ,  Clinical application of cardioactive drugs  (GW07030Y)

Reference (27)：

• 1. Shiga T, Hagiwara N, Ogawa H, Takagi A, Nagashima M, Yamauchi T, et al; Heart Institute of Japan Acute Myocardial Infarction-II (HIJAMI-II) Investigators. Sudden cardiac death and left ventricular ejection fraction during long-term follow-up after acute myocardial infarction in the primary percutaneous coronary intervention era: Results from the HIJAMI-II registry. Heart 2009; 95: 216-220.
• 2. Doughty RN, Whalley GA, Walsh HA, Gamble GD, López-Sendón J, Sharpe N; CAPRICORN Echo Substudy Investigators. Effects of carvedilol on left ventricular remodeling after acute myocardial infarction: The CAPRICORN Echo Substudy. Circulation 2004; 109: 201-206.
• 3. Sharpe N, Smith H, Murphy J, Greaves S, Hart H, Gamble G. Early prevention of left ventricular dysfunction after myocardial infarction with angiotensin-converting enzyme inhibition. Lancet 1991; 337: 872-876.
• 4. Downey JM, Cohen MV. Why do we still not have cardioprotective drugs? Circ J 2009; 73: 1171-1177.
• 5. Sterin-Borda L, Barceló AC, Bozzini CE. Erythropoietin improves cardiac contractility in post-hypoxic mice. Br J Haematol 2003; 121: 180-186.

Terms in the title (10)： 組み換え ,  静脈内投与 ,  急性心筋梗塞 ,  患者 ,  治療 ,  EPO ,  AMI ,  研究 ,  ランダム化 ,  パイロット試験