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J-GLOBAL ID：201002249572021930   Reference number：10A0490373

Cevimeline enhances the excitability of rat superior salivatory neurons

セビメリンはラット上唾液核ニューロンの興奮性を亢進する

Author (7)： UEDA Hirotaka (Dep. of Oral Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sci., Okayama Univ.) ,  UEDA Hirotaka (Dep. of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sci., Okayama Univ.) ,  MITOH Yoshihiro (Dep. of Oral Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sci., Okayama Univ.) ,  ICHIKAWA Hiroyuki (Div. of Oral and Craniofacial Anatomy, Graduate School of Dentistry, Tohoku Univ.) ,  KOBASHI Motoi (Dep. of Oral Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sci., Okayama Univ.) ,  YAMASHIRO Takashi (Dep. of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sci., Okayama Univ.) ,  MATSUO Ryuji (Dep. of Oral Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sci., Okayama Univ.)
Material： Journal of Medical Investigation  (JMI)
Volume： 56  Issue： Supplement  Page： 267-269 (J-STAGE)  Publication year： 2009 
JST Material Number： G0657A  ISSN： 1343-1420  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *oral mucosal injury preparations ,...
Semi thesaurus term： *上唾液核ニューロン

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JST classification (1)： Basic dentistry(= odontology)  (GT01020O)

Substance index (1)： Cevimeline

Reference (7)：

• 1. Matsuo R: Discharge pattern of the superior salivatory nucleus in the rat: in vivo and in vitro studies. In: Nakamura Y, Sessle BJ, eds. Neurobiology of Mastication-from Molecular to Systems Approach. Elsevier, Amsterdam, 1999, pp. 139-148
• 2. Contreras RJ, Gomez MM, Norgren R: Central origins of cranial nerve parasympathetic neurons in the rat. J Comp Neurol 190: 373-394, 1980
• 3. Hiura T: Salivatory neurons innervate the submandibular and sublingual glands in the rat: horseradish peroxidase study. Brain Res 137: 14514-9, 1977
• 4. Nicholson JE, Severin CM: The superior and inferior salivatory nuclei in the rat. Neurosci Lett 21: 149-154, 1981
• 5. Iga Y, Arisawa H, Ogane N, Saito Y, Tomizuka T, Nakagawa-Yagi Y, Masunaga H, Yasuda H, Miyata N: (+/-)-cis-2-methylspiro[1,3-oxathiolane-5,3’-quinuclidine] hydrochloride, hemihydrate (SNI-2011, cevimeline hydrochloride) induces saliva and tear secretions in rats and mice: the role of muscarinic acetylcholine receptors. Jpn J Pharmacol 78: 373-380, 1998

Terms in the title (6)： セビメリン ,  ラット ,  上唾液核 ,  ニューロン ,  興奮性 ,  亢進