Art

J-GLOBAL ID：201002260798302013   Reference number：10A0996421

Interplay between I308 and Y310 residues in the third repeat of microtubule-binding domain is essential for tau filament formation

微小管結合ドメインの第三反復におけるI308とY310残基間の相互作用はτフィラメント形成に必要不可欠である

Author (7)： NARUTO Keiko (Dep. of Physical Chemistry, Osaka Univ. of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-11, JPN) ,  MINOURA Katsuhiko (Dep. of Physical Chemistry, Osaka Univ. of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-11, JPN) ,  OKUDA Ryouhei (Dep. of Physical Chemistry, Osaka Univ. of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-11, JPN) ,  TANIGUCHI Taizo (Behavioral and Medical Sciences Res. Consortium, 2-5-7 Tamachi, Akashi, Hyogo 673-0025, JPN) ,  IN Yasuko (Dep. of Physical Chemistry, Osaka Univ. of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-11, JPN) ,  ISHIDA Toshimasa (Dep. of Physical Chemistry, Osaka Univ. of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-11, JPN) ,  TOMOO Koji (Dep. of Physical Chemistry, Osaka Univ. of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-11, JPN)
Material： FEBS Letters  (for the Rapid Publication of Short Reports in Biochemistry, Biophysics)
Volume： 584  Issue： 19  Page： 4233-4236  Publication year： Oct. 08, 2010 
JST Material Number： D0575A  ISSN： 0014-5793  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： binding site ,  Amino Acid Sequence ,  amino acid residue ,  *tau protein ,  Amyloid ,  *filament ,  time dependence ,  electron microscopy ,  base pair substitution ,  Protein Engineering ,  Polymerization ,  repetitive sequence ,  DNA ,  beta-structure ,  steric conformation ,  *microtubule ,  oligopeptide ,  oligomer ,  helix structure ,  nucleotide sequence ,  Amino Acid Substitution ,  hexapeptide ,  amyloid fiber ,  Proteins ,  glycoprotein ,  animal protein
Semi thesaurus term： amyloid fibril ,  微小管結合ドメイン

JST classification (1)： Proteins and peptides in general  (EB03010N)

Terms in the title (5)： 微小管 ,  結合ドメイン ,  反復 ,  相互作用 ,  フィラメント