Art

J-GLOBAL ID：201002285419346710   Reference number：10A0682854

Analysis of HLA-DRB1 polymorphisms in Japanese patients with primary biliary cirrhosis (PBC): The HLA-DRB1polymorphism determines the relative risk of antinuclear antibodies for disease progression in PBC

原発性胆汁性肝硬変(PBC)の日本人患者におけるHLA-DRB1遺伝子多型の分析:HLA-DRB1遺伝子多型はPBCの疾患進行に対する抗核抗体の相対リスクを決定する

Author (18)： NAKAMURA Minoru (National Hospital Organization (NHO) Nagasaki Medical Center) ,  NAKAMURA Minoru (Nagasaki Univ. Graduate School of Biomedical Sci.) ,  NAKAMURA Minoru (Headquarters of PBC Res. in the National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)) ,  YASUNAMI Michio (Nagasaki Univ.) ,  KONDO Hisayoshi (Nagasaki Univ. Graduate School of Biomedical Sci., Nagasaki) ,  HORIE Hitomi (Nagasaki Univ.) ,  AIBA Yoshihiro (National Hospital Organization (NHO) Nagasaki Medical Center) ,  KOMORI Atsumasa (National Hospital Organization (NHO) Nagasaki Medical Center) ,  KOMORI Atsumasa (Nagasaki Univ. Graduate School of Biomedical Sci.) ,  MIGITA Kiyoshi (National Hospital Organization (NHO) Nagasaki Medical Center) ,  MIGITA Kiyoshi (Nagasaki Univ. Graduate School of Biomedical Sci.) ,  YATSUHASHI Hiroshi (National Hospital Organization (NHO) Nagasaki Medical Center) ,  YATSUHASHI Hiroshi (Nagasaki Univ. Graduate School of Biomedical Sci.) ,  ITO Masahiro (National Hospital Organization (NHO) Nagasaki Medical Center) ,  ITO Masahiro (Nagasaki Univ. Graduate School of Biomedical Sci.) ,  SHIMODA Shinji (Kyushu Univ. Graduate School of Medical Sci., Fukuoka, JPN) ,  ISHIBASHI Hiromi (National Hospital Organization (NHO) Nagasaki Medical Center) ,  ISHIBASHI Hiromi (Nagasaki Univ. Graduate School of Biomedical Sci.)
Material： Hepatology Research  (Hepatol Res)
Volume： 40  Issue： 5  Page： 494-504  Publication year： May. 2010 
JST Material Number： W1284A  ISSN： 1386-6346  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： serodiagnosis ,...

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JST classification (2)： Digestive system diseases  (GH03000W) ,  Molecular genetics in general  (EC02010J)

Reference (41)：

• SCHEUER, PJ. Primary biliary cirrhosis. Proc R Soc Med. 1967, 60, 1257-1260
• RUBIN, E. Primary biliary cirrhosis. Am J Pathol. 1965, 46, 387-407
• LEUNG, PSC. Antimitochondrial antibodies in primary biliary cirrhosis. Semin Liver Dis. 1997, 17, 61-69
• COURVALIN, JC. Nuclear envelope protein autoantibodies in primary biliary cirrhosis. Semin Liver Dis. 1997, 17, 79-90
• INVERNIZZI, P. Antinuclear antibodies in primary biliary cirrhosis. Semin Liver Dis. 2005, 25, 298-310

Terms in the title (10)： 原発性胆汁性肝硬変 ,  PBC ,  日本人 ,  患者 ,  HLA-DRB1 ,  遺伝子多型 ,  分析 ,  疾患進行 ,  抗核抗体 ,  相対リスク