Art

J-GLOBAL ID：201002285769882933   Reference number：10A0534911

Mutant huntingtin impairs Ku70-mediated DNA repair

突然変異体ハンチンチンはKu70仲介DNA修復を損なう

Author (18)： ENOKIDO Yasushi (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  TAMURA Takuya (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  ITO Hikaru (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  ARUMUGHAN Anup (Max-Delbrueck Center for Molecular Medicine, Berlin-Buch, DEU) ,  KOMURO Akihiko (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  SHIWAKU Hiroki (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  SONE Masaki (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  FOULLE Raphaele (Max-Delbrueck Center for Molecular Medicine, Berlin-Buch, DEU) ,  SAWADA Hirohide (Kobe Tokiwa Univ., Kobe, JPN) ,  ISHIGURO Hiroshi (Carna Biosciences, Kobe, JPN) ,  ONO Tetsuya (Tohoku Univ., Sendai, JPN) ,  MURATA Miho (National Center for Neurology and Psychiatry, Tokyo, JPN) ,  KANAZAWA Ichiro (National Center for Neurology and Psychiatry, Tokyo, JPN) ,  TOMILIN Nikolai (Inst. Cytology, RAS, St. Petersburg, RUS) ,  TAGAWA Kazuhiko (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  WANKER Erich E. (Max-Delbrueck Center for Molecular Medicine, Berlin-Buch, DEU) ,  OKAZAWA Hitoshi (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  OKAZAWA Hitoshi (JST-PRESTO-CREST, Kawaguchi, JPN)
Material： Journal of Cell Biology  (JCB)
Volume： 189  Issue： 3  Page： 425-443  Publication year： May. 03, 2010 
JST Material Number： C0575A  ISSN： 0021-9525  CODEN： JCLBA3  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *DNA binding protein ,  DNA Repair ,  *Proteins ,  mutant ,  DNA double strand break ,  protein kinase ,  Mus musculus ,  experimental disease ,  Huntington's disease ,  Brain ,  DNA-dependent Protein Kinase ,  *Ku70 ,  *huntingtin ,  Myomorpha

JST classification (2)： Biological function  (EB03040U) ,  Molecular genetics in general  (EC02010J)

Terms in the title (5)： 突然変異体 ,  ハンチンチン ,  Ku70 ,  仲介 ,  DNA修復