Research theme for competitive and other funds (17):
2019 - 2025 ライブセルオミクスと細胞系譜解析によるパーシスタンスの理解と制御
2019 - 2025 微細流路培養による生体外での共生進化大腸菌解析
2019 - 2022 Quantitative understanding of self-replication of cells
2017 - 2022 Quantitative Analysis of fluctuation-response relationship in experimental evolution of E. coli
2016 - 2020 Competition of neutral bacteria populations in a perfusion system and its statistical physics analysis
2015 - 2020 Macroscopic Theory for Robustness and Plasticity in Cells
2015 - 2018 Understanding adaptive roles of gene expression noise by manipulating noise and heredity levels
2016 - 2017 Study of the gene regulatory network of ES cells by long-term single cell analysis using a microfluidic device
2014 - 2016 The analysis of phenotypic plasticity between the nitrogen fixation and the toxic production abilities in cyanobacteria using a single-cell device
2013 - 2016 Extracting environment-independent cellular growth properties based on phenomenological growth laws
2012 - 2015 Analysis on cell filament and phenotypic plasticity of Eschericia coli using microfluid system
2009 - 2013 バクテリアのパーシスタンス現象と原始的な表現型適応
2010 - 2011 Analysis on cell filament formation and phenotypic plasticity of Escherichia coli using micro fluid system : rapid adaptation
2009 - 2011 Differentiation response of stem cells in noisy induction environments
2009 - 2011 Single-cell microscopy with stimulus and response device to analyze relaxation mechanism of ES cells fluctuation
2009 - 2010 確率的遺伝子発現のロバストな現象論とその実験検証
2003 - 2005 1細胞計測を用いた細胞の表現型のダイナミックな変化の解析
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Papers (37):
Ken-ichiro F. Kamei, Koseki J. Kobayashi-Kirschvink, Takashi Nozoe, Hidenori Nakaoka, Miki Umetani, Yuichi Wakamoto. Raman spectra and gene expression correspondences reveal global stoichiometry conservation architecture in cells. 2023
Shunpei Yamauchi, Takashi Nozoe, Reiko Okura, Edo Kussell, Yuichi Wakamoto. A unified framework for measuring selection on cellular lineages and traits. eLife. 2022. 11
Ryuichi Koga, Minoru Moriyama, Naoko Onodera-Tanifuji, Yoshiko Ishii, Hiroki Takai, Masaki Mizutani, Kohei Oguchi, Reiko Okura, Shingo Suzuki, Yasuhiro Gotoh, et al. Single mutation makes Escherichia coli an insect mutualist. Nature Microbiology. 2022. 7. 8. 1141-1150
Yuta Koganezawa, Miki Umetani, Moritoshi Sato, Yuichi Wakamoto. History-dependent physiological adaptation to lethal genetic modification under antibiotic exposure. eLife. 2022. 11