Rchr
J-GLOBAL ID:201101020872525634
Update date: Nov. 05, 2024
WAKAMOTO Yuichi
ワカモト ユウイチ | WAKAMOTO Yuichi
Affiliation and department:
Job title:
Professor
Homepage URL (2):
http://park.itc.u-tokyo.ac.jp/wakamoto-lab/index_j.html
,
http://park.itc.u-tokyo.ac.jp/wakamoto-lab/index_e.html
Research field (1):
Bio-, chemical, and soft-matter physics
Research keywords (19):
Cancer
, パーシスタンス
, 適応
, 細胞分裂
, 進化
, 細胞系統樹
, 成長
, 微生物学
, ES細胞
, 1細胞計測
, 分化
, 発現制御
, 生物物理
, マイクロ・ナノデバイス
, モデル化
, 応答特性
, 一細胞培養
, 微細加工
, 表現型ゆらぎ
Research theme for competitive and other funds (18):
- 2024 - 2028 適応的耐性を実現する表現型可塑性と適応進化
- 2019 - 2025 ライブセルオミクスと細胞系譜解析によるパーシスタンスの理解と制御
- 2019 - 2025 微細流路培養による生体外での共生進化大腸菌解析
- 2019 - 2022 Quantitative understanding of self-replication of cells
- 2017 - 2022 Quantitative Analysis of fluctuation-response relationship in experimental evolution of E. coli
- 2016 - 2020 Competition of neutral bacteria populations in a perfusion system and its statistical physics analysis
- 2015 - 2020 Macroscopic Theory for Robustness and Plasticity in Cells
- 2015 - 2020 Understanding adaptive roles of gene expression noise by manipulating noise and heredity levels
- 2016 - 2017 Study of the gene regulatory network of ES cells by long-term single cell analysis using a microfluidic device
- 2014 - 2016 The analysis of phenotypic plasticity between the nitrogen fixation and the toxic production abilities in cyanobacteria using a single-cell device
- 2013 - 2016 Extracting environment-independent cellular growth properties based on phenomenological growth laws
- 2012 - 2015 Analysis on cell filament and phenotypic plasticity of Eschericia coli using microfluid system
- 2009 - 2013 バクテリアのパーシスタンス現象と原始的な表現型適応
- 2009 - 2012 Differentiation response of stem cells in noisy induction environments
- 2010 - 2011 Analysis on cell filament formation and phenotypic plasticity of Escherichia coli using micro fluid system : rapid adaptation
- 2009 - 2011 Single-cell microscopy with stimulus and response device to analyze relaxation mechanism of ES cells fluctuation
- 2009 - 2010 確率的遺伝子発現のロバストな現象論とその実験検証
- 2003 - 2005 1細胞計測を用いた細胞の表現型のダイナミックな変化の解析
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Papers (40):
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Ken-ichiro F. Kamei, Reiko Okura, Koseki J. Kobayashi-Kirschvink, Yuki Katayama, Yuichi Wakamoto. Raman spectra identify heterogeneous vancomycin resistance and transcriptomes of Staphylococcus aureus. bioRxiv. 2024
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Ken-ichiro F. Kamei, Koseki J. Kobayashi-Kirschvink, Takashi Nozoe, Hidenori Nakaoka, Miki Umetani, Yuichi Wakamoto. Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns. bioRxiv. 2023
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Yuta Koganezawa, Yuichi Wakamoto, Moritoshi Sato, Miki Umetani. Detecting Photoactivatable Cre-mediated Gene Deletion Efficiency in Escherichia coli. BIO-PROTOCOL. 2023. 13. 11
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Shunpei Yamauchi, Takashi Nozoe, Reiko Okura, Edo Kussell, Yuichi Wakamoto. A unified framework for measuring selection on cellular lineages and traits. eLife. 2022. 11
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Ryuichi Koga, Minoru Moriyama, Naoko Onodera-Tanifuji, Yoshiko Ishii, Hiroki Takai, Masaki Mizutani, Kohei Oguchi, Reiko Okura, Shingo Suzuki, Yasuhiro Gotoh, et al. Single mutation makes Escherichia coli an insect mutualist. Nature Microbiology. 2022. 7. 8. 1141-1150
more...
MISC (28):
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北井朝子, 若本祐一, 若本祐一, 若本祐一, 梅谷実樹, 梅谷実樹, 梅谷実樹. Effect of expression induction and protein degradation tags on gene expression noise. 日本細菌学雑誌(Web). 2023. 78. 1
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亀井健一郎, 小林鉱石, 野添嵩, 中岡秀憲, 若本祐一. Raman-omics correspondence reveals stoichiometric balance constraints on omics changes. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
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梅谷実樹, 梅谷実樹, 梅谷実樹, 橋本幹弘, 大倉玲子, 古澤力, 古澤力, 若本祐一, 若本祐一, 若本祐一. Non-genetic enhancement of resistance in Escherichia coli exposed to sublethal antibiotic stress. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
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UMETANI Miki, KOGANEZAWA Yuta, SATO Moritoshi, WAKAMOTO Yuichi. Adaptation to genetic modification in Escherichia coli. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
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若本祐一. ラマン分光を用いた細胞内の遺伝子発現の推定. 実験医学増刊「機械学習を生命科学に使う!」. 2020. 38. 20. 3376-3383
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Patents (4):
Books (2):
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定量生物学 : 生命現象を定量的に理解するために. (小林徹也編)
化学同人 2018 ISBN:9784759817300
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Controlling Cell Migration with Micropatterns. In: Innovations in Biotechnology
InTech 2012 ISBN:9789535100966
Education (3):
- 2003 - 2006 The University of Tokyo Graduate School of Arts and Sciences
- 2001 - 2003 The University of Tokyo Graduate School of Arts and Sciences
- 1997 - 2001 The University of Tokyo College of Arts and Sciences Department of Basic Science
Professional career (1):
- Ph.D. (University of Tokyo)
Work history (5):
- 2022/04 - 現在 東京大学 大学院総合文化研究科 広域科学専攻 相関基礎科学系 教授
- 2008/04 - 2022/03 東京大学 大学院総合文化研究科 広域科学専攻 相関基礎科学系 准教授
- 2009/10 - 2013/03 科学技術振興機構さきがけ 研究員(兼任)
- 2007/07 - 2008/03 スイス連邦工科大学ローザンヌ校 博士研究員
- 2006/04 - 2007/06 ロックフェラー大学 博士研究員
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