Manabe Takayuki

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Homepage URL (1)： http://www.chukyogakuin-u.ac.jp/teachers/nursing-teacher/index.html

Research field (2)： Neuroscience - general , Neuroanatomy and physiology

Research keywords (16)： HMGA1 , PS2V , ノックアウトマウス , ノックダウン , siRNA , 転写調節因子 , 脳損傷 , アストロサイト , 分化 , 小胞体ストレス , 神経分化 , ES , アセチルコリン , Lhx8 , GABA , L3

Research theme for competitive and other funds (9)：

2015 - 2018 Elucidation of the mechanism of onset of schizophrenia caused by aberrant splicing and development of novel RNA medicine
2012 - 2014 hnRNPA1 as a new neural cell differentiation development regulator -Aim at psychiatric disorder medical treatment-
2013 - 2014 神澤医学研究振興財団:研究助成
2012 - 2013 ひと・健康・未来研究財団:研究助成
2009 - 2010 統合失調症における髄鞘の分化・発達異常と選択的スプライシング因子hnRNPA1

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Papers (70)：

Megumi Furukawa, Nobuo Izumo, Takayuki Manabe, Haruna Kurono, Kohsuke Hayamizu, Makoto Nakano, Yasuo Watanabe. Therapeutic effects of sertraline on improvement of Ovariectomy-induced decreased spontaneous activity in mice. Drug Discoveries & Therapeutics. 2021. 15. 1. 28-34
Nobuo Izumo, Ishibashi Yukiko, Nobuharu Kagaya, Megumi Furukawa, Rina Iwasaki, Akihide Sumino, Kohsuke Hayamizu, Makoto Nakano, Tatsuo Hoshino, Haruna Kurono, et al. Lactoferrin suppresses decreased locomotor activities by improving dopamine and serotonin release in the amygdala of ovariectomized rats. Current Molecular Pharmacology. 2020. 13
Takashi Iezaki, Tetsuhiro Horie, Kazuya Fukasawa, Makoto Kitabatake, Yuka Nakamura, Gyujin Park, Yuki Onishi, Kakeru Ozaki, Takashi Kanayama, Manami Hiraiwa, et al. Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis. Stem Cell Reports. 2018. 11. 1. 228-241
Microtuble-associated protein 1B rescues memory decline in Alzheimer's disease model mice. 2018. 2. 1. 001-006
Izumo N, Ishibashi Y, Ono Y, Toho M, Sumino A, Kameyama T, Morikawa T, Shiba Y, Watanabe Y, Manabe T. MU134, a novel selective estrogen receptor modulator (SERM), improves estrogen-dependent depressive behaviors. Global Drugs and Therapeutics. 2017. 2. 5. 1-5

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MISC (53)：

柴裕子, 森川智美, 眞部孝幸. アルツハイマー病におけるPS2V研究の新展開. 脳21. 2016
Y. Miyatake, M. Taniguchi, S. Matsuzaki, M. Tohyama, T. Manabe, T. Katayama. The expression and the intracellular localization of Delta E2 which is novel splice variant of Disrupted-In-Schizophrenia 1 (DISC1). MOLECULAR BIOLOGY OF THE CELL. 2014. 25
宮武祐樹, 谷口学, 松崎伸介, 松崎伸介, 松崎伸介, 遠山正彌, 遠山正彌, 眞部孝幸, 片山泰一. 精神疾患リスク分子Disc1新規splice variant ΔE2は発現局在・時期がFull Lengthと異なる. 日本脳科学会プログラム・講演抄録集. 2014. 41st
宮武祐樹, 眞部孝幸, 谷口学, 松崎伸介, 松崎伸介, 遠山正彌, 遠山正彌, 遠山正彌, 片山泰一. 神経発達関連因子DISC1新規splice variant ΔE2の発現時期・細胞内局在. 日本RNA学会年会要旨集. 2014. 16th
Yukiko Ishibashi, Tomomi Morikawa, Takayuki Manabe, Michio Kimura, Nobuo Izumo. Fluvoxamine improves voluntary activity mediated by serotonin level in amygdala in OVX rats. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 188P-188P

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Professional career (1)：

Work history (20)：

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Committee career (14)：

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Association Membership(s) (3)：

日本解剖学会 , 日本薬理学会 (学術評議員) , 日本神経化学会(評議員)

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