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J-GLOBAL ID：201102221198736500   Reference number：11A0845283

Efficacy and safety of single-dose mizoribine for patients with rheumatoid arthritis: results at 6 months after switching from a multiple-dose regimen without a change in total daily dose

関節リウマチ患者に対するミゾリビン単独投与の有効性と安全性:一日量を変えずに多剤投与法からの変更後6か月間の結果

Author (8)： NISHIMURA Keita (Teikyo Univ. School of Medicine, Tokyo, JPN) ,  NISHINO Jinju (Teikyo Univ. School of Medicine, Tokyo, JPN) ,  KOUCHI Akira (Teikyo Univ. School of Medicine, Tokyo, JPN) ,  NAKAMURA Naotsugu (Teikyo Univ. School of Medicine, Tokyo, JPN) ,  NAKAJIMA Shin (Teikyo Univ. School of Medicine, Tokyo, JPN) ,  YOKOE Isamu (Itabashi Chuo Medical Center, Tokyo, JPN) ,  HARAOKA Hitomi (Itabashi Chuo Medical Center, Tokyo, JPN) ,  MATSUSHITA Takashi (Teikyo Univ. School of Medicine, Tokyo, JPN)
Material： Modern Rheumatology  (Mod Rheumatol)
Volume： 21  Issue： 2  Page： 158-163  Publication year： 2011 
JST Material Number： L5142A  ISSN： 1439-7595  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： effectiveness ,...
Semi thesaurus term： *rheumatoid arthritis ,...

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JST classification (1)： Drug therapy(=pharmacotherapy)for musculoskeletal diseases  (GG05020D)

Substance index (1)： Mizoribine

Reference (21)：

• ISHIKAWA, H. Mizoribine and mycophenolate mofetil. Curr Med Chem. 1999, 6, 575-597
• TSUJINO, M. Effect of mizoribine on adjuvant and collagen arthritis rat. Jpn J Inflamm. 1990, 10, 63-66
• ISHIKAWA, H. Effect of mizoribine on adjuvant arthritis in rat. Jpn J Inflamm. 1991, 11, 507-511
• SAIDA, K. Long-term open-trial of mizoribine with prednisolone in 24 patients with multiple sclerosis : safety, clinical and magnetic resonance imaging outcome. Intern Med. 1999, 38, 636-642
• SHIOKAWA, Y. Clinical effectiveness of mizoribine on rheumatoid arthritis : a double-blind comparative study using lobenzarit disodium as a standard drug. Jpn J Inflamm. 1991, 11, 375-396

Terms in the title (8)： 関節リウマチ ,  患者 ,  ミゾリビン ,  単独投与 ,  有効性 ,  安全性 ,  一日量 ,  多剤投与