Art

J-GLOBAL ID：201102223418728964   Reference number：11A1040272

Induction by mercury compounds of metallothioneins in mouse tissues: inorganic mercury accumulation is not a dominant factor for metallothionein induction in the liver

マウス組織中メタロチオネインの水銀化合物による誘導:無機水銀蓄積は肝におけるメタロチオネイン誘導に対する支配的因子ではない

Author (2)： YASUTAKE Akira (Biochemistry Section, National Inst. for Minamata Disease) ,  NAKAMURA Masaaki (Dep. of Clinical Medicine, National Inst. for Minamata Disease)
Material： Journal of Toxicological Sciences  (J Toxicol Sci)
Volume： 36  Issue： 3  Page： 365-372 (J-STAGE)  Publication year： 2011 
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： inorganic mercury

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JST classification (2)： Basic medicine on digestive system  (GH01020E) ,  Toxicity of metals and metal compounds  (GZ02022V)

Substance index (1)： Methylmercury

Reference (17)：

• ASCHNER, M. Brain, kidney and liver 203Hg-methyl mercury uptake in the rat : relationship to the neutral amino acid carrier. Pharmacol. Toxicol. 1989, 65, 17-20
• HIRAYAMA, K. Effects of combined administration of thiol compounds and methylmercury chloride on mercury distribution in rats. Biochem. Pharmacol. 1985, 34, 2030-2032
• HIRAYAMA, K. Effects of reactive oxygen modulators on in vivo demethylation of methylmercury. J. Health Sci. 1999, 45, 24-27
• MORI, N. Comparative study of activities in reactive oxygen species production/defense system in mitochondria of rat brain and liver, and their susceptibility to methylmercury toxicity. Arch. Toxicol. 2007, 81, 769-776
• MORI, N. Methylmercury inhibits electron transport chain activity and induces cytochrome c release in cerebellum mitochondria. J. Toxicol. Sci. 2011, 36, 253-259

Terms in the title (10)： マウス ,  組織 ,  メタロチオネイン ,  水銀化合物 ,  誘導 ,  無機水銀 ,  蓄積 ,  肝 ,  支配 ,  因子