Art

J-GLOBAL ID：201102252050378267   Reference number：11A0407425

RPAP3 enhances cytotoxicity of doxorubicin by impairing NF-kappa B pathway

RPAP3はNF-κB経路の損傷によりドキソルビシンの細胞毒性を増強する

Author (8)： SHIMADA Kana (Dep. of Pharmacology, Graduate School of Dentistry, Osaka Univ., Suita, Osaka, JPN) ,  SHIMADA Kana (Dep. of Oral & Maxillofacial Surgery II, Osaka Univ., JPN) ,  SAEKI Makio (Dep. of Pharmacology, Graduate School of Dentistry, Osaka Univ., Suita, Osaka, JPN) ,  EGUSA Hiroshi (Dep. of Fixed Prosthodontics, Osaka Univ., JPN) ,  FUKUYASU Sho (Dep. of Fixed Prosthodontics, Osaka Univ., JPN) ,  YURA Yoshiaki (Dep. of Oral & Maxillofacial Surgery II, Osaka Univ., JPN) ,  IWAI Kazuhiro (Dep. of Biophysics and Biochemistry, Graduate School of Medicine and Cell Biology and Metabolism Group, Graduate ...) ,  KAMISAKI Yoshinori (Dep. of Pharmacology, Graduate School of Dentistry, Osaka Univ., Suita, Osaka, JPN)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 404  Issue： 4  Page： 910-914  Publication year： Jan. 28, 2011 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Proteins ,  NF-kappaB ,  *cytotoxicity ,  RNA Polymerase II ,  Ubiquitination ,  intermolecular interaction ,  Apoptosis ,  leptin ,  phosphorylation ,  amino sugar ,  quinone ,  glycoside (except carbohydrate) ,  polyphenol ,  deoxysugar ,  pyranoside ,  phenol ether ,  polynuclear aromatic compound ,  hydroxy ketone ,  polyol ,  Signal Transduction ,  I kappa B kinase gamma ,  protein-protein interaction
Semi thesaurus term： cellular signal transduction ,  *RPAP3 ,  NEMO ,  protein interaction

JST classification (2)： Function of cell components  (EF03060C) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Doxorubicin

Terms in the title (5)： NF-κB経路 ,  損傷 ,  ドキソルビシン ,  細胞毒性 ,  増強