Rchr
J-GLOBAL ID：201201007009119548
Update date: Sep. 25, 2024
Hida Yasuhiro
ヒダ ヤスヒロ | Hida Yasuhiro
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
http://kaken.nii.ac.jp/d/r/30399919.ja.html
Research field (3)：
Respiratory surgery
, General surgery, pediatric surgery
, Digestive surgery
Research keywords (13)：
診断・治療バイオマーカー
, 血管新生
, 癌
, 血管内皮細胞
, 転移
, 血管新生阻害
, 血管内皮
, 腫瘍
, 微小環境
, 臨床試験
, 腫瘍血管新生
, 進行再発癌
, 腫瘍血管内皮細胞
Research theme for competitive and other funds (29)：
- 2022 - 2025 がん特異的糖鎖抗原を用いた小児がんに対する近赤外光線免疫療法の確立:前臨床モデル
- 2021 - 2024 Development of new anti-cancer strategy via activation of immunity by targeting tumor endothelial factors
- 2021 - 2024 腫瘍特異的血管新生阻害剤とドラッグリポジショニングによる新規肺癌治療の開発
- 2021 - 2024 Development of photoimmunotherapy via O-glycans and siRNA delivery system using iRGD nanoparticles in lung cancer
- 2021 - 2024 Clinical study of SARS-CoV-2 and related viruses using CPC as virus inactivator
- 2021 - 2024 がんと腫瘍血管の相互作用による新たな転移促進機構の解明とその制御
- 2018 - 2021 high-throughput screening for tumor endothelial cell specific inhibitors
- 2018 - 2021 Elucidation of the mechanism for cancer metastasis induced by oral cancer exosome and development of novel therapy for metastatic cancer
- 2018 - 2021 蛍光スペクトル解析胸腔鏡と5-ALAを応用した新規肺腫瘍マーキング法の開発
- 2018 - 2021 Basic research for elucidation of the mechanisms of tumor metastasis by tumor endothelial cells
- 2017 - 2020 Targeting urothelial cancer by inhibiting drug transporter of tumor blood vessels
- 2015 - 2018 Development of next generation lung cancer treatment targeting tumor vascular specific markers
- 2014 - 2017 Application of tumor endothelial derived exosomal-miRNA for cancer diagnosis and therapy.
- 2014 - 2017 Identification of cancer stem cell niche in oral cancer and their therapeutic application
- 2013 - 2016 Comprehensive analyses of the mechanism of bone destruction by oral cancer
- 2012 - 2016 Development of the drugs targeting lung tumor endothelial cells and the companion diagnosis
- 2012 - 2014 Investigation of the mechanism of enhanced lung metastasis due to exosome from tumor endothelial cells
- 2011 - 2014 腫瘍血管内皮細胞の幹細胞性と薬剤耐性獲得機構との関わりの解明
- 2011 - 2013 Discovery of diagonositc and therapeutic biomarker by circulating tumor endothelial cells in metastatic renal cell carcinoma
- 2012 - 2012 非小細胞肺癌幹細胞における分泌型miRNAの同定とその治療応用へ向けての解析
- 2011 - 2012 Targeting tumor metastasis by normalization of tumor blood vessels
- 2009 - 2011 Mechanism of premetastatic niche formation and promotion of metastasis by cancer mesenchymal cells
- 2009 - 2011 Application of EPC for tissue regeneration
- 2009 - 2010 血管新生阻害療法に対する腫瘍血管内皮細胞の抵抗性獲得の機序解析
- 2008 - 2010 Development of novel antiangiogenic therapy based on tumor microenviroenment
- 2006 - 2007 Clinical trial of cancer vaccine using NY-ESO-1/CpG
- 2006 - 2007 Clarify of the mechanism of anti-angiogenesis by PEDF and clinical application of PEDF gene therapy
- 2006 - 2007 The significance of endothelial progenitor cell as a tumor marker in PBMC
- 2006 - 2007 Analysis of Tumor-associated Endothelial Cell Biology
Show all
Papers (227)：
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Aki Fujiwara-Kuroda, Masato Aragaki, Yasuhiro Hida, Hideki Ujiie, Kazuto Ohtaka, Haruhiko Shiiya, Kichizo Kaga, Tatsuya Kato. A simple and safe surgical technique for nonpalpable lung tumors: One-stop Solution for a nonpalpable lung tumor, Marking, Resection, and Confirmation of the surgical margin in a Hybrid operating room (OS-MRCH). Translational lung cancer research. 2024. 13. 3. 603-611
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桜井 優弥, 間石 奈湖, 藤岡 容一郎, 大場 雄介, 武田 遼, 佐々木 道仁, 大場 靖子, 樋田 泰浩, 澤 洋文, 樋田 京子. 血管内皮細胞におけるSARS-CoV-2侵入機構の解析(Analysis of SARS-CoV-2 uptake mechanism in vascular endothelial cells). 日本病理学会会誌. 2024. 113. 1. 369-369
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Takuya Tsumita, Ryo Takeda, Nako Maishi, Yasuhiro Hida, Michihito Sasaki, Yasuko Orba, Akihiko Sato, Shinsuke Toba, Wataru Ito, Takahito Teshirogi, et al. Viral uptake and pathophysiology of the lung endothelial cells in age-associated severe SARS-CoV-2 infection models. Aging Cell. 2023. e14050
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Li Yu, Yuying Hong, Nako Maishi, Aya Yanagawa Matsuda, Yasuhiro Hida, Akira Hasebe, Yoshimasa Kitagawa, Kyoko Hida. Oral bacterium Streptococcus mutans promotes tumor metastasis through thrombosis formation. Cancer science. 2023
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Seiki Hasegawa, Yasushi Shintani, Teruhisa Takuwa, Keisuke Aoe, Katsuya Kato, Nobukazu Fujimoto, Yasuhiro Hida, Masahiro Morise, Yasumitsu Moriya, Takao Morohoshi, et al. Nationwide prospective registry database of patients with newly diagnosed untreated pleural mesothelioma in Japan. Cancer science. 2023
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MISC (737)：
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桜井優弥, 間石奈湖, 藤岡容一朗, 大場雄介, 武田遼, 佐々木道仁, 大場靖子, 樋田泰浩, 澤洋文, 澤洋文, et al. 血管内皮細胞におけるSARS-CoV-2侵入機構の解析. 日本血管生物医学会学術集会プログラム・抄録集. 2023. 31st (CD-ROM)
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LI Y U, 間石奈湖, 赤堀永倫香, 長谷部晃, 武田遼, 松田彩, 樋田泰浩, 北川善政, 樋田京子. Vascular inflammation induced by oral bacteria Streptococcus mutans promote tumor metastasis. 日本がん転移学会学術集会・総会プログラム抄録集. 2023. 32nd
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武田遼, 武田遼, 伊藤航, 手代木孝仁, 佐々木道仁, 大場靖子, 大場靖子, 間石奈湖, 松田彩, 佐藤彰彦, et al. SARS-CoV-2感染マウスを用いた肺血管内皮細胞の重症化関連遺伝子の解析. 日本血管生物医学会学術集会プログラム・抄録集. 2022. 30th (CD-ROM)
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藤原晶, 長島諒太, 千葉龍平, 田畑佑希子, 氏家秀樹, 加藤達哉, 樋田泰浩, 加賀基知三. 当科における単孔式複雑区域切除術の経験. 日本呼吸器外科学会総会(Web). 2022. 39th
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藤原晶, 樋田泰浩, 山崎雅久, 千葉龍平, 野村俊介, 武藤潤, 氏家秀樹, 加賀基知三, 加藤達哉. Hybrid手術室を利用した触知不能病変の同定と切除マージンの確認法の工夫. 日本胸部外科学会定期学術集会(Web). 2022. 75th
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Patents (8)：
Education (2)：
- 1995 - 2000 Hokkaido University Graduate School of Medicine Surgical Oncology
- 1985 - 1991 Hokkaido University School of Medicine
Professional career (1)：
Work history (4)：
- 2022/09 - 現在 Fujita Health University Advanced robotic and endoscopic surgery Professor
- 2015/10 - 2022/08 Hokkaido University Hokkaido University Hospital Associate professor
- 2005/12 - 2015/09 Hokkaido University
- 2001/03 - 2005/05 Children's hospital, Harvard university
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