Takahashi Nobunori

Research field (1)： Orthopedics

Research theme for competitive and other funds (11)：

2023 - 2026 ヒアルロン酸レセプターCD44の断片化阻害による、関節軟骨変性抑制効果
2021 - 2024 活性値の乖離に着目した血友病性関節症の病態解明とアンメットニーズの開拓
2021 - 2024 Analysis of joint regeneration mechanism by secretory sialic acid recognition lectin
2019 - 2022 Development of a new therapeutic drug for osteoarthritis that has a cartilage-protecting effect by inhibiting Wnt/ADAM10
2020 - 2021 外因性hyaluronanの軟骨細胞における役割の解明

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Papers (80)：

Yoshifumi Ohashi, Nobunori Takahashi, Yasumori Sobue, Mochihito Suzuki, Ryo Sato, Masataka Maeda, Daisuke Kihira, Kenji Kishimoto, Kenya Terabe, Shuji Asai, et al. Associations of frailty with RA-ILD and poor control of disease activity in patients with rheumatoid arthritis: A multi-center retrospective observational study. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. 2023
Yoshifumi Ohashi, Nobunori Takahashi, Yasumori Sobue, Mochihito Suzuki, Ryo Sato, Masataka Maeda, Kenya Terabe, Shuji Asai, Shiro Imagama. Well-controlled disease activity with drug treatment will not improve the frailty status of RA patients to robust state: A multicenter observational study (T-FLAG). International journal of rheumatic diseases. 2023
Kenji Kishimoto, Toshihisa Kojima, Nobunori Takahashi, Shuji Asai, Kenya Terabe, Mochihito Suzuki, Yoshifumi Ohashi, Daisuke Kihira, Masataka Maeda, Masahiro Tatebe, et al. Periprosthetic humeral fracture revision using a massive allograft in a patient with rheumatoid arthritis: A case report. Modern rheumatology case reports. 2023. 7. 2. 359-363
Kenya Terabe, Nobunori Takahashi, Shuji Asai, Yuji Hirano, Yasuhide Kanayama, Yuichiro Yabe, Takeshi Oguchi, Takayoshi Fujibayashi, Hisato Ishikawa, Masahiro Hanabayashi, et al. Effectiveness of tacrolimus concomitant with biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis. Modern rheumatology. 2023. 33. 2. 292-301
Daihei Kida, Hiroya Hashimoto, Noriko Ito, Yukari Kito, Kouichi Mori, Yosuke Hattori, Nobunori Takahashi, Masaaki Matsubara. Patient-Specific Femoral Guide with 3-Dimensional Support Software in Anterolateral Supine Approach of Total Hip Arthroplasty: A Single-Arm Trial. The Kurume medical journal. 2023. 68. 1. 1-8

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MISC (59)：

Takahashi N, Kojima T, Kida D, Kaneko A, Hirano Y, Fujibayashi T, Yabe Y, Takagi H, Oguchi T, Hanabayashi M, et al. Clinical effectiveness and long-term retention of abatacept in elderly rheumatoid arthritis patients: Results from a multicenter registry system. Modern rheumatology. 2018. 1-23
Kida D, Hashimoto H, Ito N, Kito Y, Mori K, Takahashi N, Tomita Y. An Open-Label, Single-Arm Study of a Patient-Specific Femoral Guide for Total Hip Arthroplasty via the Anterolateral Supine Approach, Linked with Three-Dimensional Surgical Support Software: Study Protocol. The Kurume medical journal. 2018. 65. 2. 71-75
Asai S, Nagai K, Takahashi N, Watanabe T, Matsumoto T, Asai N, Sobue Y, Ishiguro N, Kojima T. Influence of methotrexate on gastrointestinal symptoms in patients with rheumatoid arthritis. International journal of rheumatic diseases. 2018
Kida D, Hashimoto H, Saito AM, Kito Y, Mori K, Terabe K, Takahashi N, Tomita Y. An Open-label Single-arm Trial of a Novel Extramedullary Guide Coordinated with 3D Surgical Assistive Software for Total Knee Arthroplasty. Acta medica Okayama. 2018. 72. 4. 441-445
Shuji Asai, Takayoshi Fujibayashi, Takeshi Oguchi, Masahiro Hanabayashi, Masatoshi Hayashi, Hiroyuki Matsubara, Takayasu Ito, Yuichiro Yabe, Tsuyoshi Watanabe, Yuji Hirano, et al. Predictors of biologic discontinuation due to insufficient response in patients with rheumatoid arthritis who achieved clinical remission with biologic treatment: A multicenter observational cohort study. Modern Rheumatology. 2018. 28. 2. 221-226

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Lectures and oral presentations (35)：

ヒアルロン酸とCD44
(第26回日本整形外科学会基礎学術集会 2011)
生物学的製剤使用中に悪性リンパ腫を併発した関節リウマチ患者4例における検討
(第23回中部リウマチ学会 2011)
インフリキシマブ増量プロトコール導入後の治療成績
(第55回日本リウマチ学会 2011)
Superficial zone chondrocytes from bovine articular cartilage respond predominately to exogenous BMP-7
(57th Annual Meeting of Orthopaedic Research Society 2011)
牛関節軟骨細胞において表層部細胞は、中間部/深部細胞と比較して強いBMP-7への反応性を示す
(第24回日本軟骨代謝学会 2011)

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Education (2)：

2002 - 2006 Nagoya University Graduate School, Division of Medical Sciences
- 1997 Nagoya University Faculty of Medicine

Professional career (1)：

Doctor (medicine) (Nagoya University)

Work history (6)：

2015/05/01 - 現在 Nagoya University Orthopedic Surgery, Hospital
2013/07/01 - 2015/04/30 Nagoya University Orthopedic Surgery, Hospital
2011/08/01 - 2013/06/30 Nagoya University Orthopedic Surgery, Hospital
2009/07/01 - 2011/07/31 名古屋医療センター整形外科
2007/04/01 - 2009/06/30 East Caroline University

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Committee career (1)：

2012/04/01 - 現在臨床系コア・カリキュラムワーキンググループ委員

Association Membership(s) (5)：

Orthopedic Research Society , International Society for Hyaluronan Sciences , 日本軟骨代謝学会 , 日本リウマチ学会 , 日本整形外科学会

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