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J-GLOBAL ID：201802233731935614   Reference number：18A0731142

Predictors of biologic discontinuation due to insufficient response in patients with rheumatoid arthritis who achieved clinical remission with biologic treatment: A multicenter observational cohort study

生物学的処理で臨床的寛解を達成した関節リウマチ患者における不十分な応答による生物学的中断の予測因子:多施設観察コホート研究

Author (21)： ASAI Shuji (Nagoya Univ. Graduate School of Medicine, Aichi, JPN) ,  FUJIBAYASHI Takayoshi (Konan Kosei Hospital, Aichi, JPN) ,  OGUCHI Takeshi (Anjo Kosei Hospital, Aichi, JPN) ,  HANABAYASHI Masahiro (Ichinomiya Municipal Hospital, Aichi, JPN) ,  HAYASHI Masatoshi (Nagano Red Cross Hospital, Nagano, JPN) ,  MATSUBARA Hiroyuki (Nagano Red Cross Hospital, Nagano, JPN) ,  ITO Takayasu (Ito Orthopedic Clinic, Aichi, JPN) ,  YABE Yuichiro (Tokyo Shinjuku Medical Center, Tokyo, JPN) ,  WATANABE Tsuyoshi (Kariya-Toyota General Hospital, Aichi, JPN) ,  HIRANO Yuji (Toyohashi Municipal Hospital, Aichi, JPN) ,  KANAYAMA Yasuhide (Toyota Kosei Hospital, Aichi, JPN) ,  KANEKO Atsushi (Nagoya Medical Center, Aichi, JPN) ,  KATO Takefumi (Kato Orthopedic Clinic, Aichi, JPN) ,  TAKAGI Hideki (Nagoya Central Hospital, Aichi, JPN) ,  TAKAHASHI Nobunori (Nagoya Univ. Graduate School of Medicine, Aichi, JPN) ,  FUNAHASHI Koji (Nagoya Univ. Graduate School of Medicine, Aichi, JPN) ,  TAKEMOTO Toki (Nagoya Univ. Graduate School of Medicine, Aichi, JPN) ,  ASAI Nobuyuki (Nagoya Univ. Graduate School of Medicine, Aichi, JPN) ,  WATANABE Tatsuo (Nagoya Univ. Graduate School of Medicine, Aichi, JPN) ,  ISHIGURO Naoki (Nagoya Univ. Graduate School of Medicine, Aichi, JPN) ,  KOJIMA Toshihisa (Nagoya Univ. Graduate School of Medicine, Aichi, JPN)
Material： Modern Rheumatology  (Mod Rheumatol)
Volume： 28  Issue： 2  Page： 221-226  Publication year： Mar. 2018 
JST Material Number： L5142A  ISSN： 1439-7595  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human ,...

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JST classification (1)： Drug therapy(=pharmacotherapy)for musculoskeletal diseases  (GG05020D)

Reference (19)：

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• Smolen JS, Nash P, Durez P, Hall S, Ilivanova E, Irazoque-Palazuelos F, et al. Maintenance, reduction, or withdrawal of etanercept after treatment with etanercept and methotrexate in patients with moderate rheumatoid arthritis (PRESERVE): a randomised controlled trial. Lancet. 2013;381:918-29.
• Smolen JS, Emery P, Fleischmann R, van Vollenhoven RF, Pavelka K, Durez P, et al. Adjustment of therapy in rheumatoid arthritis on the basis of achievement of stable low disease activity with adalimumab plus methotrexate or methotrexate alone: the randomised controlled OPTIMA trial. Lancet. 2014;383:321-32.
• Tanaka Y, Hirata S, Kubo S, Fukuyo S, Hanami K, Sawamukai N, et al. Discontinuation of adalimumab after achieving remission in patients with established rheumatoid arthritis: 1-year outcome of the HONOR study. Ann Rheum Dis. 2015;74:389-95.

Terms in the title (12)： 生物学的処理 ,  臨床的寛解 ,  関節リウマチ ,  患者 ,  応答 ,  生物学 ,  中断 ,  予測因子 ,  施設 ,  観察 ,  コホート ,  研究