Rchr
J-GLOBAL ID:201201090285537340   Update date: Nov. 24, 2024

ADACHI Noritaka

アダチ ノリタカ | ADACHI Noritaka
Affiliation and department:
Other affiliations (1):
Homepage URL  (1): http://dnar.sci.yokohama-cu.ac.jp/
Research field  (4): Cell biology ,  Molecular biology ,  Genetics ,  Pharmaceuticals - health and biochemistry
Research keywords  (15): ヒトゲノム ,  老化 ,  がん ,  細胞周期 ,  組換え ,  DNA修復 ,  分子生物学 ,  Aging ,  Human Genome ,  Cancer Chemotherapy ,  Cancer Genetics ,  Cell Cycle ,  DNA Recombination ,  DNA Repair ,  Molecular Biology
Research theme for competitive and other funds  (26):
  • 2022 - 2024 条件的遺伝子発現系の理論的構築による新規DNA修復欠損がん診断・治療戦略の開発
  • 2019 - 2023 生体環境からみたゲノム組換え修復に関する包括的理解
  • 2018 - 2020 Efficient suppression of random DNA integration
  • 2015 - 2018 Development of high-efficiency gene targeting technologies
  • 2014 - 2016 Genes that enable high-efficiency gene disruption in human cells
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Papers (103):
  • Yuduki Someya, Shinta Saito, Shigeki Takeda, Noritaka Adachi, Aya Kurosawa. Quercetin exhibits cytotoxicity in cancer cells by inducing two-ended DNA double-strand breaks. Biochemical and Biophysical Research Communications. 2024. 739. 150977-150977
  • Shinta Saito, Noritaka Adachi. Characterization and regulation of cell cycle-independent noncanonical gene targeting. Nature Communications. 2024. 15. 1. 5044-5044
  • Tadaaki Nakajima, Akihiro Imai, Chihiro Ishii, Kota Tsuruyama, Risa Yamanaka, Yasuhiro Tomooka, Shinta Saito, Noritaka Adachi, Satomi Kohno, Tomomi Sato. SMAD2/3 signaling regulates initiation of mouse Wolffian ducts and proximal differentiation in Müllerian ducts. FEBS Open Bio. 2023
  • Aya Kurosawa, Shinta Saito, Mikiko Sakurai, Mizuki Shinozuka, Yuduki Someya, Noritaka Adachi. Arsenic affects homologous recombination and single-strand annealing but not end-joining pathways during DNA double-strand break repair. The FEBS Journal. 2023
  • Yuduki Someya, Sakine Kobayashi, Kazuya Toriumi, Shigeki Takeda, Noritaka Adachi, Aya Kurosawa. A Cell System-Assisted Strategy for Evaluating the Natural Antioxidant-Induced Double-Stranded DNA Break (DSB) Style. Genes. 2023. 14. 2
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MISC (52):
  • 斎藤 慎太, 足立 典隆. 【分子標的薬を極める-基礎から臨床まで-】分子標的薬の基礎 相同組換え修復. 産科と婦人科. 2020. 87. 10. 1138-1144
  • 黒沢 綾, 高橋 昭久, 武田 茂樹, 柴田 淳史, 足立 典隆. 高LET線ならびに放射線類似薬により誘発されるDNA二本鎖切断の修復における修復経路の重要度の解析(Requirement of DNA double-strand break repair pathways for repairing high LET radiation- and radiomimetic agents-induced DNA damage). 日本放射線影響学会大会講演要旨集. 2020. 63回. 75-75
  • 足立 典隆. 研究者の最新動向 ランダム挿入反応の分子機構と完全阻害. Precision Medicine. 2020. 3. 6. 590-593
  • 坂本裕太, 斎藤慎太, 足立典隆. Functional analysis of human WHSC1 in DNA double-strand break repair. 日本環境変異原学会大会プログラム・要旨集. 2020. 49th (CD-ROM)
  • 斎藤慎太, 足立典隆. DNA polymerase θ is essential for alternative end-joining. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
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Patents (3):
Books (2):
  • Complete suppression of random integration in human cells
    2019
  • 進化するゲノム編集技術
    NTS 2015
Education (2):
  • The University of Tokyo Graduate School of Pharmaceutical Sciences
  • The University of Tokyo Faculty of Pharmaceutical Sciences
Professional career (1):
  • 博士(薬学) (東京大学)
Work history (2):
  • 南カリフォルニア大学医学部
  • Yokohama City University
Association Membership(s) (3):
日本薬学会 ,  日本癌学会 ,  日本分子生物学会
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