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J-GLOBAL ID：201202223177179740   Reference number：12A0439251

Mutations to create thermostable reverse transcriptase with bacterial family A DNA polymerase from Thermotoga petrophila K4

Thermotoga petrophila K4由来の細菌科DNAポリメラーゼを持つ熱安定性逆転写酵素を創造するための突然変異

Author (7)： SANO Sotaro ,  YAMADA Yosuke ,  SHINKAWA Tomoki ,  KATO Satoru ,  OKADA Takashi ,  HIGASHIBATA Hiroki ,  FUJIWARA Shinsuke
Material： Journal of Bioscience and Bioengineering
Volume： 113  Issue： 3  Page： 315-321  Publication year： Mar. 2012 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *bacterium ,...
Semi thesaurus term： *Thermotoga petrophila ,...

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JST classification (3)： Enzyme in general  (EB09010D) ,  Microorganism biochemistry  (EG03020N) ,  Molecular genetics in general  (EC02010J)

Reference (26)：

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• KIM, B. New human immunodeficiency virus, type 1 reverse transcriptase (HIV-1 RT) mutants with increased fidelity of DNA synthesis. Accuracy, template binding, and processivity. J. Biol. Chem. 1999, 274, 27666-27673
• AREZI, B. Escherichia coli DNA polymerase III epsilon subunit increases Moloney murine leukemia virus reverse transcriptase fidelity and accuracy of RT-PCR procedures. Anal. Biochem. 2007, 360, 84-91
• YASUKAWA, K. Comparison of the thermal stabilities of reverse transcriptases from avian myeloblastosis virus and Moloney murine leukaemia virus. J. Biochem. 2008, 143, 261-268
• AREZI, B. Novel mutations in Moloney murine leukemia virus reverse transcriptase increase thermostability through tighter binding to template-primer. Nucleic Acids Res. 2009, 37, 473-481

Terms in the title (6)： 細菌 ,  DNAポリメラーゼ ,  熱安定性 ,  逆転写酵素 ,  創造 ,  突然変異