Art

J-GLOBAL ID：201202240628875934   Reference number：12A0268556

Constituents from the Roots of Taraxacum platycarpum and Their Effect on Proliferation of Human Skin Fibroblasts

Taraxacum platycarpumの根茎からの構成成分およびヒト皮膚線維芽細胞の増殖へのそれらの影響

Author (3)： WARASHINA Tsutomu (Inst. for Environmental Sciences, Univ. of Shizuoka) ,  UMEHARA Kaoru (School of Pharmaceutical Sciences, Univ. of Shizuoka) ,  MIYASE Toshio (School of Pharmaceutical Sciences, Univ. of Shizuoka)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 60  Issue： 2  Page： 205-212 (J-STAGE)  Publication year： 2012 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： fibroblast ,  growth factor ,  Cell Proliferation ,  *pentacyclic triterpene ,  *sesquiterpene ,  *glycoside (except carbohydrate) ,  biological sample analysis ,  extraction liquid ,  *dandelion ,  Rhizome ,  skin fibroblast
Semi thesaurus term： Taraxacum platycarpum

JST classification (1)： Triterpenes  (CF10024I)

Substance index (19)： (17S)-3β-Acetoxy-17,18-secolupa-19(21)-ene-18,22-dione ,  (18α,19α)-30-(Hydroperoxy)-5α-urs-20-ene-3β-ol acetate ,  (3S)-3β-(β-D-Glucopyranosyloxy)-3,3aβ,4,5,9aβ,9bα-hexahydro-3,6,9-trimethylazuleno[4,5-b]furan-2,7-dione ,  2,8-Dimethyl-4α-(β-D-glucopyranosyloxy)-6α-hydroxy-10-oxobicyclo[5.3.0]decane-1,8-diene-5β-[(αS)-α-hydroxy-α-(hydroxymethyl)acetic acid]γ-lactone ,  21α-Hydroperoxytaraxerylacetate ,  3β-Acetoxy-11α-hydroperoxyoleana-12-ene ,  3β-Acetoxy-11-(hydroperoxymethylene)-5α-lupa-12-ene ,  3β-Acetoxy-5α-lupa-12-ene-11-one ,  α-Amyrin acetate ,  β-Amyrin acetate ,  Ixerin D ,  Dihydrosyringin ,  Cichorioside C ,  Deacetylmatricarin 8-O-β-D-glucopyranoside ,  Neoilexonol acetate ,  Lupeol acetate ,  φ-Taraxasteryl acetate ,  Taraxasterol acetate ,  Ptiloepoxyl acetate

Reference (21)：

• 1) Hori M., Ito K., Ansai K., Kojima K., Jpn. Kokai Tokkyo Koho, CODEN: JKXXAF JP 10036279 A 19980210 AN 2009 : 1421926 CAPLUS (1998).
• 2) Shiojima K., Masuda K., Suzuki H., Lin T., Ooishi Y., Ageta H., Chem. Pharm. Bull., 43, 1634—1639 (1995).
• 3) Menichini F., Benedetto R. D., Monache F. D., Phytochemistry, 41, 1377—1379 (1996).
• 4) Kuo Y.-H., Chiang Y.-M., Chem. Pharm. Bull., 48, 593—596 (2000).
• 5) Ito K., Lai J., Yakugaku Zasshi, 98, 249—256 (1978).

Terms in the title (6)： Taraxacum ,  根茎 ,  構成成分 ,  ヒト ,  皮膚線維芽細胞 ,  増殖