Art

J-GLOBAL ID：201202242559083780   Reference number：12A0024422

Endoplasmic reticulum stress enhances γ-secretase activity

小胞体ストレスはγセクレターゼ活性を増強する

Author (16)： OHTA Kazunori (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  MIZUNO Akihito (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  LI Shimo (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  ITOH Masanori (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  UEDA Masashi (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  OHTA Eri (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  HIDA Yoko (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  WANG Miao-xing (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  FUROI Manabu (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  TSUZUKI Yukihiro (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  SOBAJIMA Mitsuaki (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  BOHMOTO Yoshimasa (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  FUKUSHIMA Tatsuya (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  KOBORI Masuko (National Food Res. Inst., National Agriculture and Food Res. Organization, Tsukuba, Ibaraki, JPN) ,  INUZUKA Takashi (Dep. of Neurology and Geriatrics, Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  NAKAGAWA Toshiyuki (Dep. of Neurobiology, Gifu Univ. Graduate School of Medicine, Gifu, JPN)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 416  Issue： 3-4  Page： 362-366  Publication year： Dec. 16, 2011 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *ER stress ,  *aspartic proteinase ,  *cell physiology ,  *protein processing ,  cellular signal transduction ,  route ,  endoplasmic reticulum ,  Alzheimer disease ,  pathogenesis ,  risk factor ,  obesity ,  diabetes mellitus ,  stress(physiology) ,  DNA binding protein ,  transcription factor ,  presenilin ,  gene expression ,  amyloid beta-protein ,  secretion(physiology) ,  ketone ,  oxygen heterocyclic compound ,  polyphenol ,  flavonoid ,  polynuclear aromatic compound ,  hydroxy ketone ,  type 2 diabetes mellitus
Semi thesaurus term： non-insulin-dependent diabetes mellitus ,  Activating transcription factor-4 ,  *gamma-secretase ,  signal transfer ,  signal transduction pathway ,  presenilin-1 ,  Intracellular signaling ,  transcription factor 4 ,  *Unfold protein response

JST classification (6)： Cell physiology in general  (EF02010S) ,  Enzyme in general  (EB09010D) ,  Metabolism in general  (EB03050F) ,  Cell components in general  (EF03010Z) ,  Nervous system diseases  (GN03000O) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (1)： Quercetin

Terms in the title (4)： 小胞体ストレス ,  γセクレターゼ ,  活性 ,  増強