Art

J-GLOBAL ID：201202253515784112   Reference number：12A0189867

Enhanced transdermal delivery of indomethacin using combination of PLGA nanoparticles and iontophoresis in vivo

ポリ(ラクチド-co-グリコリド)(PLGA)ナノ粒子とin vivoイオン泳動法を結合することによるインドメタシンの増強された経皮デリバリー

Author (12)： TOMODA Keishiro (Fac. of Pharmaceutical Sciences, Tokyo Univ. of Sci., 2641 Yamazaki, Noda, Chiba 278-8510, JPN) ,  TOMODA Keishiro (Center for Drug Delivery Res., Fac. of Pharmaceutical Sciences, Tokyo Univ. of Sci., 2641 Yamazaki, Noda, Chiba ...) ,  TOMODA Keishiro (Center for Physical Pharmaceutics, Tokyo Univ. of Sci., 2641 Yamazaki, Noda, Chiba 278-8510, JPN) ,  TERASHIMA Hiroto (Fac. of Pharmaceutical Sciences, Tokyo Univ. of Sci., 2641 Yamazaki, Noda, Chiba 278-8510, JPN) ,  SUZUKI Kenichi (Pharmaceutical Div., Kowa Co., Ltd., 332-1 Ohnoshinden, Fuji, Shizuoka 417-8650, JPN) ,  INAGI Toshio (Pharmaceutical Div., Kowa Co., Ltd., 4-14 Nihonbashi-honcho 3-chome, Chuo-ku, Tokyo 103-8433, JPN) ,  TERADA Hiroshi (Fac. of Pharmaceutical Sciences, Tokyo Univ. of Sci., 2641 Yamazaki, Noda, Chiba 278-8510, JPN) ,  TERADA Hiroshi (Center for Drug Delivery Res., Fac. of Pharmaceutical Sciences, Tokyo Univ. of Sci., 2641 Yamazaki, Noda, Chiba ...) ,  TERADA Hiroshi (Center for Physical Pharmaceutics, Tokyo Univ. of Sci., 2641 Yamazaki, Noda, Chiba 278-8510, JPN) ,  MAKINO Kimiko (Fac. of Pharmaceutical Sciences, Tokyo Univ. of Sci., 2641 Yamazaki, Noda, Chiba 278-8510, JPN) ,  MAKINO Kimiko (Center for Drug Delivery Res., Fac. of Pharmaceutical Sciences, Tokyo Univ. of Sci., 2641 Yamazaki, Noda, Chiba ...) ,  MAKINO Kimiko (Center for Physical Pharmaceutics, Tokyo Univ. of Sci., 2641 Yamazaki, Noda, Chiba 278-8510, JPN)
Material： Colloids and Surfaces. B. Biointerfaces  (Colloids Surf B Biointerfaces)
Volume： 92  Page： 50-54  Publication year： Apr. 01, 2012 
JST Material Number： W0541A  ISSN： 0927-7765  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *ionophoresis ,  *nano particle ,  *poly(lactic-glycolic acid) ,  *drug delivery system ,  *percutaneous absorption ,  permeability ,  nitrogen heterocyclic compound ,  aromatic carboxylic acid ,  aromatic chlorine compound ,  carboxamide ,  phenol ether ,  polynuclear aromatic compound ,  enzyme inhibitor
Semi thesaurus term： *PLGA ,  *PLGAナノ粒子 ,  *Transdermal delivery

JST classification (2)： Polymer carrier,catalytic reaction  (CG03030W) ,  Physical pharmacy  (GY01012A)

Substance index (1)： Indomethacin

Terms in the title (9)： ラクチド ,  CO ,  グリコリド ,  PLGA ,  ナノ粒子 ,  イオン泳動法 ,  インドメタシン ,  増強 ,  経皮デリバリー