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J-GLOBAL ID：201202254938849063   Reference number：12A1340548

Synthesis and Structure-Activity Relationship Study of Antimicrotubule Agents Phenylahistin Derivatives with a Didehydropiperazine-2,5-dione Structure

ジデヒドロピペラジン-2,5-ジオン構造を有する抗微小管薬剤フェニラヒスチン誘導体の合成および構造活性相関研究

Author (24)： YAMAZAKI Yuri (Tokyo Univ. of Pharmacy and Life Sci., Tokyo, JPN) ,  YAMAZAKI Yuri (Kyoto Pharmaceutical Univ., Kyoto, JPN) ,  TANAKA Koji (Kyoto Pharmaceutical Univ., Kyoto, JPN) ,  NICHOLSON Benjamin (Nereus Pharmaceuticals, California, USA) ,  DEYANAT-YAZDI Gordafaried (Nereus Pharmaceuticals, California, USA) ,  POTTS Barbara (Nereus Pharmaceuticals, California, USA) ,  YOSHIDA Tomoko (Kyoto Pharmaceutical Univ., Kyoto, JPN) ,  ODA Akiko (Kyoto Pharmaceutical Univ., Kyoto, JPN) ,  KITAGAWA Takayoshi (Kyoto Pharmaceutical Univ., Kyoto, JPN) ,  ORIKASA Sumie (Kyoto Pharmaceutical Univ., Kyoto, JPN) ,  KISO Yoshiaki (Kyoto Pharmaceutical Univ., Kyoto, JPN) ,  YASUI Hiroyuki (Kyoto Pharmaceutical Univ., Kyoto, JPN) ,  AKAMATSU Miki (Kyoto Univ., Kyoto, JPN) ,  CHINEN Takumi (Univ. of Tsukuba, Tsukuba, JPN) ,  USUI Takeo (Univ. of Tsukuba, Tsukuba, JPN) ,  SHINOZAKI Yuki (Tokyo Univ. of Pharmacy and Life Sci., Tokyo, JPN) ,  YAKUSHIJI Fumika (Tokyo Univ. of Pharmacy and Life Sci., Tokyo, JPN) ,  MILLER Brian R. (Nereus Pharmaceuticals, California, USA) ,  NEUTEBOOM Saskia (Nereus Pharmaceuticals, California, USA) ,  PALLADINO Michael (Nereus Pharmaceuticals, California, USA) ,  KANOH Kaneo (Marine Biotechnology Inst. Co., Ltd., Iwate, JPN) ,  LLOYD George Kenneth (Nereus Pharmaceuticals, California, USA) ,  HAYASHI Yoshio (Tokyo Univ. of Pharmacy and Life Sci., Tokyo, JPN) ,  HAYASHI Yoshio (Kyoto Pharmaceutical Univ., Kyoto, JPN)
Material： Journal of Medicinal Chemistry  (J Med Chem)
Volume： 55  Issue： 3  Page： 1056-1071  Publication year： Feb. 09, 2012 
JST Material Number： D0102A  ISSN： 0022-2623  CODEN： JMCMAR  Document type： Article
Country of issue： United States (USA)  Language： ENGLISH (EN)

Terms in the title (7)： ジオン ,  微小管 ,  薬剤 ,  フェニラヒスチン ,  誘導体 ,  構造活性相関 ,  研究