Art

J-GLOBAL ID：201202260096564006   Reference number：12A0103334

Development of a solid-supported biotinylation reagent for efficient biotin labeling of SH groups on small molecules

小分子上SH基の効率的ビオチン標識のための固体担持ビオチニル化試薬の開発

Author (7)： FUKUMOTO Kentarou (Dep. of Medicinal Chemistry, Tokyo Univ. of Pharmacy and Life Sciences, Hachioji 192-0392, JPN) ,  FUKUMOTO Kentarou (Kokusan Chemical Co., Ltd, Tokyo 103-0023, JPN) ,  ADACHI Kumi (Dep. of Medicinal Chemistry, Tokyo Univ. of Pharmacy and Life Sciences, Hachioji 192-0392, JPN) ,  KAJIYAMA Akihiro (Dep. of Medicinal Chemistry, Tokyo Univ. of Pharmacy and Life Sciences, Hachioji 192-0392, JPN) ,  YAMAZAKI Yuri (Dep. of Medicinal Chemistry, Tokyo Univ. of Pharmacy and Life Sciences, Hachioji 192-0392, JPN) ,  YAKUSHIJI Fumika (Dep. of Medicinal Chemistry, Tokyo Univ. of Pharmacy and Life Sciences, Hachioji 192-0392, JPN) ,  HAYASHI Yoshio (Dep. of Medicinal Chemistry, Tokyo Univ. of Pharmacy and Life Sciences, Hachioji 192-0392, JPN)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 53  Issue： 5  Page： 535-538  Publication year： Feb. 01, 2012 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： reagent ,  *biotinylation ,  *mercapto group ,  molecular design ,  amino acid ,  thiol ,  nitrogen heterocyclic compound ,  carboxamide ,  carrier reagent
Semi thesaurus term： *SH group ,  biotinylation

JST classification (1)： Research methods in biological sciences in general  (EA03010K)

Substance index (2)： Captopril ,  3-[6-[2-[5-[(3aβ,6aβ)-2-Oxohexahydro-1H-thieno[3,4-d]imidazole-4α-yl]pentanoylamino]ethyldithio]-5-nitro-3-pyridylcarbonylamino]propionic acid

Terms in the title (8)： 小分子 ,  SH基 ,  ビオチン標識 ,  固体 ,  担持 ,  ビオチニル化 ,  試薬 ,  開発