Art

J-GLOBAL ID：201202262827405100   Reference number：12A1632447

Effects of Hypoxia-inducible Factor-1α Chemical Stabilizer, CoCl₂ and Hypoxia on Gene Expression of CYP3As in Human Fetal Liver Cells

ヒト胎児肝細胞におけるCYP3Aの遺伝子発現に及ぼす低酸素誘導因子-1α化学安定剤,CoCl2および低酸素の作用

Author (9)： SUZUKI Eiji (Dep. of Molecular Pharmacology, Shinshu Univ. Graduate School of Medicine) ,  SUZUKI Eiji (Dep. of Pharmacy, Nagano Municipal Hospital) ,  MATSUNAGA Tamihide (Dep. of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City Univ.) ,  AONUMA Akiko (Dep. of Molecular Pharmacology, Shinshu Univ. Graduate School of Medicine) ,  AONUMA Akiko (Dep. of Pharmacy, Shinshu Univ. Hospital) ,  SASAKI Takamitsu (Dep. of Environmental and Health Sci., Tohoku Pharmaceutical Univ.) ,  NAGATA Kiyoshi (Dep. of Environmental and Health Sci., Tohoku Pharmaceutical Univ.) ,  OHMORI Shigeru (Dep. of Molecular Pharmacology, Shinshu Univ. Graduate School of Medicine) ,  OHMORI Shigeru (Dep. of Pharmacy, Shinshu Univ. Hospital)
Material： Drug Metabolism and Pharmacokinetics  (Drug Metab Pharmacokinet)
Volume： 27  Issue： 4  Page： 398-404 (J-STAGE)  Publication year： 2012 
JST Material Number： X0758A  ISSN： 1347-4367  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： hepatocyte ,...
Semi thesaurus term： Cytochrome P-450 CYP3A ,...

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JST classification (1)： Basic biopharmacy  (GY01021U)

Reference (28)：

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• 5) Lacroix, D., Sonnier, M., Moncion, A., Cheron, G. and Cresteil, T.: Expression of CYP3A in the human liver—evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth. Eur. J. Biochem., 247: 625–634 (1997).

Terms in the title (10)： ヒト ,  胎児 ,  肝細胞 ,  CYP3A ,  遺伝子発現 ,  低酸素誘導因子 ,  化学 ,  安定剤 ,  COCl2 ,  低酸素