Art

J-GLOBAL ID：201202278160869700   Reference number：12A0703493

ENANTIOSELECTIVE SYNTHESIS OF ε-LACTONES BY LIPASE-CATALYZED RESOLUTION

リパーゼで触媒された光学分割によるε-カプロラクトン類のエナンチオ選択的合成

Author (4)： SHIMOTORI Yasutaka (Kitami Inst. of Technol., Hokkaido, JPN) ,  AOYAMA Masakazu (Kitami Inst. of Technol., Hokkaido, JPN) ,  TSUKASA Hidetaka (Toyotama International Inc., Tokyo, JPN) ,  MIYAKOSHI Tetsuo (Meiji Univ., Kawasaki, JPN)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 85  Issue： 5  Page： 1061-1075  Publication year： May. 01, 2012 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *racemic modification ,  *optical resolution ,  lipase ,  *enzyme availed reaction ,  Acylation ,  carboxamide ,  Hydrolysis ,  hydroxy acid ,  cyclization reaction ,  *lactone ,  lactonization ,  reaction mechanism ,  fatty acid ,  aliphatic alcohol ,  enol ester ,  vinyl compound ,  unsaturated alcohol ,  alkaline hydrolysis ,  intramolecular cyclization
Semi thesaurus term： racemic resolution ,  intramolecular cyclization reaction

JST classification (3)： Other separation methods  (CC01060D) ,  Seven-membered heterocyclic compounds  (CF07110I) ,  Nitrogen derivatives of aliphatic carboxylic acids  (CF03220A)

Substance index (10)： ε-Caprolactone ,  Acetic acid vinyl ester ,  rac-(6R^*)-N-Methyl-6-hydroxydodecaneamide ,  rac-(6R^*)-N-Benzyl-6-hydroxydodecaneamide ,  rac-(6R^*)-N-Isopropyl-6-hydroxydodecaneamide ,  rac-(6R^*)-N-Methyl-6-hydroxydecanamide ,  (R)-7-Hexyloxepane-2-one ,  (7R)-7-Butyloxepan-2-one ,  7α-Hexyloxepan-2-one ,  7α-Butyloxepan-2-one

Reference (33)：

• 1. G. Ohloff, Progress in Organic Chemistry, Springer Verlag, 1978, 35.
• 2. W. A. May, R. J. Peterson, and S. S. Chang, J. Food Sci., 1978, 43, 1248.
• 3. A. Mosandl and C. Günther, J. Agric. Food Chem., 1989, 37, 413.
• 4. A. Mosandl and M. Gessner, Z Lebensm Unters Forsch, 1988, 187, 40.
• 5. M. Furukawa, Y. Kodera, T. Uemura, M. Hiroto, A. Matsushima, H. Kuno, H. Matsushita, and Y. Inada, Biochem. Biophys. Res. Commun., 1994, 199, 41.

Terms in the title (5)： リパーゼ ,  触媒 ,  光学分割 ,  ε-カプロラクトン ,  エナンチオ選択的合成