Art

J-GLOBAL ID：201202283248776616   Reference number：12A1527513

Serum levels of soluble secreted α-Klotho are decreased in the early stages of chronic kidney disease, making it a probable novel biomarker for early diagnosis

可溶性分泌α-Klothoの血清レベルは慢性腎疾患の初期段階で低下し,初期診断の可能性のある新しいバイオマーカーになる

Author (13)： SHIMAMURA Yoshiko (Kochi Univ., Nankoku, JPN) ,  HAMADA Kazu (Kochi Univ., Nankoku, JPN) ,  INOUE Kosuke (Kochi Univ., Nankoku, JPN) ,  OGATA Koji (Kochi Univ., Nankoku, JPN) ,  ISHIHARA Masayuki (Kochi Univ., Nankoku, JPN) ,  KAGAWA Toru (Kochi Univ., Nankoku, JPN) ,  INOUE Mari (Kochi Univ., Nankoku, JPN) ,  FUJIMOTO Shimpei (Kochi Univ., Nankoku, JPN) ,  IKEBE Mika (Kochi-Takasu Hospital, Kochi, JPN) ,  YUASA Kenji (Kochi-Takasu Hospital, Kochi, JPN) ,  YAMANAKA Shigeo (Kochi Univ., Nankoku, JPN) ,  SUGIURA Teturo (Kochi Univ., Nankoku, JPN) ,  TERADA Yoshio (Kochi Univ., Nankoku, JPN)
Material： Clinical and Experimental Nephrology  (Clin Exp Nephrol)
Volume： 16  Issue： 5  Page： 722-729  Publication year： Oct. 2012 
JST Material Number： L3173A  ISSN： 1342-1751  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *Proteins ,...
Semi thesaurus term： *Klotho protein ,...

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JST classification (2)： Urologenital system diagnosis  (GM02000E) ,  Hormones,cytokines,bioactive peptides in general  (EB08010W)

Substance index (1)： Creatinine

Reference (31)：

• ZHANG, QL. Prevalence of chronic kidney disease in population-based studies : systematic review. BMC Public Health. 2008, 8, 117
• MANJUNATH, G. Level of kidney function as s risk factor for atherosclerotic cardiovascular outcomes in the community. J Am Coll Cardiol. 2003, 41, 47-55
• BAIGENT, C. Premature cardiovascular disease in chronic renal failure. Lancet. 2000, 356, 147-152
• CORESH, J. Prevalence of chronic kidney disease and decreased kidney function in the adult US population. Third National Health and Nutrition Examination Survey. Am J Kidney Dis. 2003, 41, 1-12
• CORESH, J. Prevalence of chronic kidney disease in the United States. JAMA. 2007, 298, 2038-2047

Terms in the title (8)： 可溶性 ,  分泌 ,  血清レベル ,  慢性腎疾患 ,  初期段階 ,  初期診断 ,  可能性 ,  バイオマーカー