Art

J-GLOBAL ID：201202299276889306   Reference number：12A1186415

Thyroid Dysfunction in Patients Treated with Tyrosine Kinase Inhibitors, Sunitinib, Sorafenib and Axitinib, for Metastatic Renal Cell Carcinoma

転移性腎細胞癌に対しチロシンキナーゼ阻害剤,スニチニブ,ソラフェニブおよびアキシチニブによる治療を施行された患者の甲状腺機能障害

Author (11)： DAIMON Makoto (Yamagata Univ. Fac. Medicine, Yamagata, JPN) ,  KATO Tomoyuki (Yamagata Univ. Fac. Medicine, Yamagata, JPN) ,  KAINO Wataru (Yamagata Univ. Fac. Medicine, Yamagata, JPN) ,  TAKASE Kaoru (Yamagata Univ. Fac. Medicine, Yamagata, JPN) ,  KARASAWA Shigeru (Yamagata Univ. Fac. Medicine, Yamagata, JPN) ,  WADA Kiriko (Yamagata Univ. Fac. Medicine, Yamagata, JPN) ,  KAMEDA Wataru (Yamagata Univ. Fac. Medicine, Yamagata, JPN) ,  SUSA Shinji (Yamagata Univ. Fac. Medicine, Yamagata, JPN) ,  OIZUMI Toshihide (Yamagata Univ. Fac. Medicine, Yamagata, JPN) ,  TOMITA Yoshihiko (Yamagata Univ. Fac. Medicine, Yamagata, JPN) ,  KATO Takeo (Yamagata Univ. Fac. Medicine, Yamagata, JPN)
Material： Japanese Journal of Clinical Oncology  (JJCO)
Volume： 42  Issue： 8  Page： 742-747  Publication year： Aug. 2012 
JST Material Number： W2222A  ISSN： 0368-2811  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *metastatic renal cell carcinoma ,...

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JST classification (2)： Urogenital tumors(=neoplasms)  (GM04000S) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Substance index (3)： Sunitinib ,  Sorafenib ,  Axitinib

Reference (20)：

• Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nat Rev Cancer 2009; 9: 28-39.
• Lombardi G, Zustovich F, Donach M, Dalla Palma M, Nicoletto O, Pastorelli D. An update on targeted therapy in metastatic renal cell carcinoma. Urol Oncol doi:10.1016/j.urolonc.2009.12.018.
• Torino F, Corsello SM, Longo R, Barnabei A, Gasparini G. Hypothyroidism related to tyrosine kinase inhibitors: an emerging toxic effect of targeted therapy. Nat Rev Clin Oncol 2009; 6: 219-28.
• Lacouture ME. Mechanisms of cutaneous toxicities to EGFR inhibitors. Nat Rev Cancer 2006; 6: 806-12.
• Sherman SI. Thyrosine kinase inhibitors and the thyroid. Best Pract Res Clin Endocrinol Metab 2009; 23: 713-22.

Terms in the title (8)： 転移性腎細胞癌 ,  チロシンキナーゼ阻害剤 ,  スニチニブ ,  ソラフェニブ ,  アキシチニブ ,  治療 ,  患者 ,  甲状腺機能障害