Rchr
J-GLOBAL ID：201301034786271110
Update date: Oct. 01, 2022
Masataka Ihara
イハラ マサタカ | Masataka Ihara
Affiliation and department：
Job title：
Specially Appointed Professor
Other affiliations (1)：
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株式会社シンスター・ジャパン
最高科学アドバイサー
Homepage URL (1)：
http://kaken.nii.ac.jp/d/r/00006339.ja.html
Research field (4)：
Pharmaceuticals - chemistry and drug development
, Pharmaceuticals - chemistry and drug development
, Bioorganic chemistry
, Structural/physical organic chemistry
Research keywords (32)：
Global Health
, Medicinal Chemistry
, インドールアルカロイド
, 不斉合成
, カスケード反応
, 立体選択的合成
, Organic Synthesis
, 生理活性化合物
, 生理活性天然物
, 分子内二重ミカエル反応
, アルカロイド
, ラジカル反応
, 多環状化合物
, 多連続反応
, 分子内連続反応
, 分子内ダブルミカエル反応
, 分子内ミカエル・アルドール反応
, 連続反応
, 多環性化合物
, 遷移金属触媒反応
, テルペン
, ドミノ反応
, イソキノリンアルカロイド
, ステロイド
, 極性反応
, ペリ環状反応
, ラジカル転位反応
, ホモプロトベルベリン
, 多環状有機化合物
, テルペノイド
, 生理活性物質
, インドロキノリチジン
Research theme for competitive and other funds (9)：
- 2010 - 2010 Development Candidate SSJ-183
- 2008 - 2010 Discovery of Anti-leishmaniasis and Anti-trypanosomiasis Agents
- 2005 - 2007 Discovery of Anti-protozoan Agents
- 1998 - 新規抗マラリア薬の開発
- 1998 - Development of new antimalarials
- 1970 - 有機合成法の開発
- 1970 - Developement of New Methodology for Organic Synthesis
- 1965 - Synthesis of Biologically Active Compounds
- 1965 - 生理活性物質の合成
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Papers (6)：
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Yuki Mizukawa, Jian-Feng Ge, Abu Bakar Md, Isamu Itoh, Christian Scheurer, Sergio Wittlin, Reto Brun, Hiroyuki Matsuoka, Masataka Ihara. Novel synthetic route for antimalarial benzo[a]phenoxazine derivative SSJ-183 and two active metabolites. BIOORGANIC & MEDICINAL CHEMISTRY. 2014. 22. 14. 3749-3752
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Sarah Schleiferböck, Christian Scheurer, Masataka Ihara, Isamu Itoh, Ian Bathurst, Jeremy N. Burrows, Pascal Fantauzzi, Julie Lotharius, Susan A. Charman, Julia Morizzi, et al. In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models. Drug Design, Development and Therapy. 2013. 7. 1377-1384
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Jun Lu, Chika Arai, Md Abu Bakar, Masataka Ihara. Plasmodium berghei proteome changes in response to SSJ-183 treatment. BIOORGANIC & MEDICINAL CHEMISTRY. 2011. 19. 13. 4144-4147
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Jian-Feng Ge, Chika Arai, Mei Yang, Abu Bakar Md, Jun Lu, Nasser S. M. Ismail, Sergio Wittlin, Marcel Kaiser, Reto Brun, Susan A. Charman, et al. Discovery of Novel Benzo[a]phenoxazine SSJ-183 as a Drug Candidate for Malaria. ACS MEDICINAL CHEMISTRY LETTERS. 2010. 1. 7. 360-364
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Mei Yang, Chika Arai, Abu Bakar Md, Jun Lu, Jian-Feng Ge, Khanitha Pudhom, Kiyosei Takasu, Kazuki Kasai, Marcel Kaiser, Reto Brun, et al. Fluorinated Rhodacyanine (SJL-01) Possessing High Efficacy for Visceral Leishmaniasis (VL). JOURNAL OF MEDICINAL CHEMISTRY. 2010. 53. 1. 368-373
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MISC (126)：
Works (1)：
Education (3)：
- 1967 - 1970 Tohoku University Pharmaceutical Institute PhD Course
- 1965 - 1967 Tohoku University Pharmaceutical Institute Master Course
- 1964 - 1965 Tohoku University Pharmaceutical Institute Undergraduate
Professional career (1)：
Work history (7)：
- 2006/04 - 現在 Hoshi University Drug Discovery Science Research Center Specially Appointed Professor
- 2006/03 - 現在 Tohoku University Professor emeritus of Tohoku University
- 1997/04 - 2006/03 Tohoku University Graduate School of Pharmaceutical Sciences Professor
- 2006 - Hoshi University
- 1981/05 - 1997/03 Tohoku University Faculty of Pharmaceutical Sciences Associate Professor
- 1970/04 - 1981/04 Tohoku University Faculty of Pharmaceutical Sciences Assistant Professor
- 1971/10 - 1974/03 Cambridge University Chemical Laboratory Postdoctral fellow
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Awards (4)：
- 2005 - The Pharmaceutical Society of Japan Award
- 2004 - The Kametani Award
- 1992 - The Miyata Academic Prize
- 1987 - Research Foundation Award for Pharmaceutical Sciences
Association Membership(s) (3)：
THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN
, American Chemical Society
, THE PHARMACEUTICAL SOCIETY OF JAPAN
