Okamoto Ken

オカモトケン | Okamoto Ken

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/60267143.ja.html

Research field (7)： Medical biochemistry , Pathobiochemistry , Functional biochemistry , Neuroscience - general , Neuroscience - general , Biochemistry , Structural biochemistry

Research keywords (33)：構造生物学 , molybdenum enzymes , enzyme mechanism , structural biology , enzyme inhibitors , xanthine oxidase , xanthine oxidoreductase , キサンチン脱水素酵素 , キサンチン酸化酵素 , X線結晶構造解析 , xanthine dehydrogenase , スーパーオキシド , 阻害剤 , 抗痛風薬 , キサンチン酸化還元酵素 , トランスジェニックマウス , 構造ベース創薬 , iron-sulfur center , 分子病態学 , 鉄硫黄中心 , 活性酸素 , X線結晶解析 , フラビン酵素 , 非ヘム鉄 , 金属タンパク質 , 金属フラビン酵素 , フリーラジカル , 鉄結合タンパク質 , NO合成酵素 , 結晶構造 , EPR , flavoprotein , モリブデン酵素

Papers (23)：

Ivan Sebesta, Daisuke Miyamoto, Blanka Stiburkova, Sarka Blahova, Nana Sato, Koji Nagata, Ken Okamoto, Shuichi Tsuruoka, Kimiyoshi Ichida. Modified forearm ischemic test in hypouricemic patients. Nucleosides, nucleotides & nucleic acids. 2020. 1-8
Peng Lu, Yoshitaka Moriwaki, Mimin Zhang, Yukie Katayama, Yi Lu, Ken Okamoto, Tohru Terada, Kentaro Shimizu, Mengyao Wang, Takehiro Kamiya, et al. Functional characterisation of two ferric-ion coordination modes of TtFbpA, the periplasmic subunit of an ABC-type iron transporter from Thermus thermophilus HB8. Metallomics : integrated biometal science. 2019. 11. 12. 2078-2088
Yoshitaka Moriwaki, Mirai Yato, Tohru Terada, Seiji Saito, Noriyuki Nukui, Takumi Iwasaki, Tatsunari Nishi, Yuko Kawaguchi, Ken Okamoto, Takatoshi Arakawa, et al. Understanding the Molecular Mechanism Underlying the High Catalytic Activity of p-Hydroxybenzoate Hydroxylase Mutants for Producing Gallic Acid. Biochemistry. 2019. 58. 45. 4543-4558
Teruo Kusano, Driss Ehirchiou, Tomohiro Matsumura, Veronique Chobaz, Sonia Nasi, Mariela Castelblanco, Alexander So, Christine Lavanchy, Hans Acha-Orbea, Takeshi Nishino, et al. Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth. NATURE COMMUNICATIONS. 2019. 10. 1. 4904-4904
Takashi Tani, Ken Okamoto, Megumi Fujiwara, Akira Katayama, Shuichi Tsuruoka. Metabolomics analysis elucidates unique influences on purine/pyrimidine metabolism by xanthine oxidoreductase inhibitors in a rat model of renal ischemia-reperfusion injury. MOLECULAR MEDICINE. 2019. 25. 1. 40-40

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MISC (150)：

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Professional career (1)：

医学博士

Work history (1)：

2012 - Nippon Medical School Medical School

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