Art

J-GLOBAL ID：201302226382864355   Reference number：13A0555552

The pathogenesis of ALS and stem cell therapy

筋萎縮性側索硬化症の病態解明と治療戦略

Author (2)： NAGAI MAKIKO (北里大 医 神経内科学) ,  NISHIYAMA KAZUTOSHI (北里大 医 神経内科学)
Material： 北里医学(Web)  (Kitasato Medicine (Web))
Volume： 42  Issue： 2  Page： 85-93 (WEB ONLY)  Publication year： Dec. 31, 2012 
JST Material Number： U0319A  ISSN： 0385-5449  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *Amyotrophic Lateral Sclerosis ,...
Semi thesaurus term： genetic variation ,...

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JST classification (1)： Nervous system diseases  (GN03000O)

Reference (57)：

• 1. Rosen DR, Siddique T, Patterson D, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993; 362: 59-62.
• 2. Cleveland DW. From Charcot to SOD1: mechanisms of selective motor neuron death in ALS. Neuron 1999; 24: 515-20.
• 3. Gurney ME, Pu H, Chiu AY, et al. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 1994; 264: 1772-5.
• 4. Nagai M, Aoki M, Miyoshi I, et al. Transgenic mice expressing an H46R mutant of human Cu/Zn superoxide dismutase. Molecular mechanism and therapeutics of amyotrophic lateral sclerosis. Ed by Abe K. Elsevier; Amsterdam: 2001; 273-9.
• 5. Nagai M, Aoki M, Miyoshi I, et al. Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease. J Neurosci 2001; 21: 9246-54.

Terms in the title (3)： 筋萎縮性側索硬化症 ,  病態解明 ,  治療戦略