Art

J-GLOBAL ID：201302232389775714   Reference number：13A1003113

Small Interfering RNA Targeting CD81 Decreased the Expression of Tumor Necrosis Factor-alpha and Synoviolin in SW982 Cells

低分子干渉RNA標的CD81はSW982細胞における腫瘍壊死因子αおよびシノビオリンの発現を減少させた

Author (6)： HANADA Takae (Support Office, Shujitsu Univ. School of Pharmacy) ,  FUJIMOTO Erika (Kyokuto Hospital) ,  MORI Hiroki (Fac. of Education, Shujitsu Univ.) ,  OHASHI Toshitaka (Okayama Univ. Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  NINOMIYA Yoshifumi (Okayama Univ. Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  NAKANISHI Tohru (Molecular Biology and Clinical Diagnosis, Shujitsu Univ. Graduate School of Pharmacy)
Material： Journal of Hard Tissue Biology  (J Hard Tissue Biol)
Volume： 22  Issue： 2  Page： 195-200 (J-STAGE)  Publication year： 2013 
JST Material Number： L2839A  ISSN： 1341-7649  CODEN： JHTBFF  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *CD antigen ,...
Semi thesaurus term： rheumatoid arthritis ,...

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JST classification (1)： Basic medicine on musculoskeletal system  (GG01020B)

Reference (12)：

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• 2. Toh M-L, Marotte H, Blond J-L, Jhumka U, Eljaafari A, Mougin B and Miossec P. Overexpression of synoviolin in peripheral blood and synoviocytes from rheumatoid arthritis patients and continued elevation in nonresponders to infliximab treatment. Arthr Rheumat 54: 2109-2118, 2006
• 3. Amano T, Yamasaki S, Yagishita N, Tsuchimochi K, Shin H, Kawahara K, Aratani S, Fujita H, Lei Zhang, Ikeda R, Fujii R, Miura N, Komiya S, Nishioka K, Maruyama I, Fukamizu A and Nakajima T. Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy. Genes Dev 17: 2436-2449, 2003
• 4. Yamasaki S, Yagishita N, Tsuchimochi K, Nishioka K and Nakajima T. Rheumatoid arthritis as a hyper-endoplasmic reticulum-associated degradation disease. Arthr Res Therap 7: 181-186, 2005
• 5. Kaneko M, Ishiguro M, Niinuma Y, Uesugi M and Nomura Y. Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation. Feder Europ Biochem Soc Let 532: 147-152, 2002

Terms in the title (7)： 低分子干渉RNA ,  標的 ,  CD81 ,  細胞 ,  腫瘍壊死因子 ,  シノビオリン ,  発現