Art

J-GLOBAL ID：201302234760600518   Reference number：13A1763934

Inflammatory and Necrotic Effects of Minodronate, a Nitrogen-Containing Bisphosphonate, in Mice

マウスにおける窒素含有ビスホスホネートであるミノドロネートの炎症効果と壊死効果

Author (16)： KIYAMA Tomomi (Div. of Oral Molecular Regulation, Graduate School of Dentistry, Tohoku Univ.) ,  KIYAMA Tomomi (Div. of Advanced Prosthetic Dentistry, Graduate School of Dentistry, Tohoku Univ.) ,  OKADA Satoru (Div. of Oral Molecular Regulation, Graduate School of Dentistry, Tohoku Univ.) ,  OKADA Satoru (Div. of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Tohoku Univ.) ,  TANAKA Yukinori (Div. of Oral Molecular Regulation, Graduate School of Dentistry, Tohoku Univ.) ,  KIM Siyoung (Div. of Oral Molecular Regulation, Graduate School of Dentistry, Tohoku Univ.) ,  KIM Siyoung (Div. of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku Univ.) ,  BANDO Kanan (Div. of Oral Molecular Regulation, Graduate School of Dentistry, Tohoku Univ.) ,  BANDO Kanan (Div. of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku Univ.) ,  HASEGAWA Masakazu (Div. of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku Univ.) ,  YAMAGUCHI Kouji (Div. of Oral Molecular Regulation, Graduate School of Dentistry, Tohoku Univ.) ,  YAMAGUCHI Kouji (Div. of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Tohoku Univ.) ,  TAKANO-YAMAMOTO Teruko (Div. of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku Univ.) ,  SASAKI Keiichi (Div. of Advanced Prosthetic Dentistry, Graduate School of Dentistry, Tohoku Univ.) ,  SUGAWARA Shunji (Div. of Oral Molecular Regulation, Graduate School of Dentistry, Tohoku Univ.) ,  ENDO Yasuo (Div. of Oral Molecular Regulation, Graduate School of Dentistry, Tohoku Univ.)
Material： Tohoku Journal of Experimental Medicine  (Tohoku J Exp Med)
Volume： 230  Issue： 3  Page： 141-149 (J-STAGE)  Publication year： 2013 
JST Material Number： G0649A  ISSN： 0040-8727  CODEN： TJEMAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...

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JST classification (1)： Basic research of other drugs acting on metabolism  (GW13060I)

Substance index (1)： YM-529

Reference (33)：

• ADAMI, S. The acute phase response after bisphosphonate administration. Calcif. Tissue Int. 1987, 41, 326-331
• ADAMI, S. Adverse effects of bisphosphonate. A comparative review. Drug Saf. 1996, 14, 158-170
• AMAGASE, K. Gastric ulcerogenic and healing impairment effects of risedronate, a nitrogen-containing bisphosphonate in rats. Comparison with alendronate and minodronate. J. Physiol. Pharmacol. 2011, 62, 609-618
• CHEN, J. S. Antiresorptive therapies for osteoporosis : a clinical review. Nature Rev. Endocrinol. 2012, 8, 81-91
• CREPIN, S. Osteonecrosis of the jaw induced by clodronate, an alkylbisphsophonate : case report and literature review. Eur. J. Clin. Pharmacol. 2010, 66, 547-554

Terms in the title (6)： マウス ,  窒素 ,  ビスホスホネート ,  ミノドロネート ,  炎症 ,  壊死