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J-GLOBAL ID：201302236489608276   Reference number：13A0943239

糸状菌由来エンドグリコシダーゼ(Endo-M)の新規なグライコシンターゼ様変異体の創製と糖鎖複合体の効率的合成への応用

Author (4)： UMEKAWA MIDORI (立命館大 生命科学) ,  ASHIDA HISASHI (近畿大 生物理工) ,  WANG Lai-Xi (Univ. Maryland School of Medicine) ,  YAMAMOTO KENJI (石川県大 生物資源工研)
Material： 応用糖質科学  (Bulletin of Applied Glycoscience)
Volume： 3  Issue： 2  Page： 143-150  Publication year： May. 20, 2013 
JST Material Number： L7982A  ISSN： 2185-6427  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *endo-glycosidase ,...
Semi thesaurus term： グライコシンターゼ

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JST classification (2)： Applications of enzymes  (EB09100B) ,  Genetic variation  (EC01030Y)

Reference (11)：

• YAMAMOTO, K. Transglycosylation activity of Mucor hiemalis endo-β-N-acetylglucosaminidase which transfers complex oligosaccharides to the N-acetylglucosamine moieties of peptides. Biochem. Biophys. Res. Commun. 1994, 203, 244-252
• UMEKAWA, M. Mutants of Mucor hiemalis endo-β-N-acetylglucosaminidase show enhanced transglycosylation and glycosynthase-like activities. J. Biol. Chem. 2008, 283, 4469-4479
• MACKENZIE, L. F. Glycosynthases : Mutant glycosidases for oligosaccharide synthesis. J. Am. Chem. Soc. 1998, 120, 5583-5584
• FUJITA, M. A novel disaccharide substrate having 1,2-oxazoline moiety for detection of transglycosylating activity of endoglycosidases. Biochim. Biophys. Acta. 2001, 1528, 9-14
• WILLIAMS, S. J. Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state. J. Biol. Chem. 2002, 277, 40055-40065

Terms in the title (7)： 糸状菌 ,  エンドグリコシダーゼ ,  変異体 ,  創製 ,  糖鎖 ,  複合体 ,  応用