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J-GLOBAL ID：201302258733461146   Reference number：13A0847919

Multicenter phase II study of modified FOLFOX6 as neoadjuvant chemotherapy for patients with unresectable liver-only metastases from colorectal cancer in Japan: ROOF study

日本における結腸直腸癌由来の切除不能肝限局転移患者のためのネオアジュバント化学療法としての改良FOLFOX6の多施設第II相試験 ROOF試験

Author (13)： TAKAHASHI Takao (Gifu Univ. School of Medicine, Gifu, JPN) ,  SHIBATA Yoshihisa (Toyohashi Municipal Hospital, Toyohashi, JPN) ,  TOJIMA Yuichiro (Chukyo Hospital, Nagoya, JPN) ,  TSUBOI Kenji (Tosei General Hospital, Seto, JPN) ,  SAKAMOTO Eiji (Nagoya Daini Red Cross Hospital, Nagoya, JPN) ,  KUNIEDA Katsuyuki (Giru Prefectural General Medical Center, Gifu, JPN) ,  MATSUOKA Hiroshi (Fujita Health Univ., Toyoake, JPN) ,  SUZUMURA Kazuyoshi (Aichi Medical Univ., Nagakute, JPN) ,  SATO Mikinori (Nagoya City Univ. Graduate School of Medical Sci., Nagoya, JPN) ,  NAGANUMA Tatsushi (Saiseikai Matsusaka General Hospital, Matsusaka, JPN) ,  SAKAMOTO Junichi (Nagoya Univ., Nagoya, JPN) ,  MORITA Satoshi (Yokohama City Univ. School of Medicine and Univ. Medical Center, Yokohama, JPN) ,  KONDO Ken (Nagoya Medical Center, Nagoya, JPN)
Material： International Journal of Clinical Oncology  (Int J Clin Oncol)
Volume： 18  Issue： 2  Page： 335-342  Publication year： Apr. 2013 
JST Material Number： L3966A  ISSN： 1341-9625  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *colorectal cancer ,...

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JST classification (3)： Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Reference (23)：

• FINAN, PJ. Factors affecting survival in patients presenting with synchronous hepatic metastases from colorectal cancer : a clinical and computer analysis. Br J Surg. 1985, 72, 373-377
• GOSLIN, R. Factors influencing survival in patients with hepatic metastases from adenocarcinoma of the colon or rectum. Dis Colon Rectum. 1982, 25, 749-754
• BENGTSSON, G. Natural history of patients with untreated liver metastases from colorectal cancer. Am J Surg. 1981, 141, 586-589
• FONG, Y. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer : analysis of 1001 consecutive cases. Ann Surg. 1999, 230, 309-318
• ADAM, R. Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy : a model to predict long-term survival. Ann Surg. 2004, 240, 644-657

Terms in the title (9)： 日本 ,  結腸直腸癌 ,  切除不能 ,  患者 ,  ネオアジュバント化学療法 ,  FOLFOX6 ,  施設 ,  第II相試験 ,  試験