Art

J-GLOBAL ID：201302285233773386   Reference number：13A0727682

Autoantibodies in Myasthenia Gravis

Antibody Update 重症筋無力症の自己抗体

Author (2)： MOTOMURA MASAKATSU (長崎大 病院 第一内科 神経内科) ,  NARITA(MASUDA) TOMOKO (長崎大 病院 第一内科 神経内科)
Material： Brain and Nerve  (Brain and Nerve 神経研究の進歩)
Volume： 65  Issue： 4  Page： 433-439  Publication year： Apr. 01, 2013 
JST Material Number： Z0685B  ISSN： 1881-6096  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *autoantibody ,...
Semi thesaurus term： *抗Lrp4抗体 ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=13A0727682&from=J-GLOBAL&jstjournalNo=Z0685B") }}

JST classification (3)： Nervous system diseases  (GN03000O) ,  Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Biochemistry of antigens,antibodies,complements  (ED04020L)

Reference (32)：

• 1) 本村政勝:重症筋無力症−−病原性のある自己抗体は何か. Brain Nerve 62:411-418, 2010
• 2) Lindstrom JM, Seybold ME, Lennon VA, Whittingham S, Duane DD: Antibody to acetylcholine receptor in myasthenia gravis: prevalence, clinical correlates, and diagnostic value. Neurology 26: 1054-1059, 1976
• 3) Tzartos SJ, Sophianos D, Efthimiadis A: Role of the main immunogenic region of acetylcholine receptor in myasthenia gravis: an Fab monoclonal antibody protects against antigenic modulation by human sera. J Immunol 134: 2343-2349, 1985
• 4) Luo J, Taylor P, Losen M, de Baets MH, Shelton GD, et al: Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity. J Neurosci 29: 13898-13908, 2009
• 5) Masuda T, Motomura M, Utsugisawa K, Nagane Y, Nakata R, et al: Antibodies against the main immunogenicregion of the acetylcholine receptor correlate with disease severity in myasthenia gravis. J Neurol Neurosurg Psychiatry 83: 935-940, 2012

Terms in the title (2)： 重症筋無力症 ,  自己抗体