Art

J-GLOBAL ID：201302286904979312   Reference number：13A1914565

TERT promoter mutations rather than methylation are the main mechanism for TERT upregulation in adult gliomas

メチル化よりむしろTERTプロモーター変異は、成人の神経膠腫におけるTERTのアップレギュレーションに対する主要なメカニズムである

Author (11)： ARITA Hideyuki (National Cancer Center Hospital, Dep. of Neurosurgery and Neuro-Oncology, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, JPN) ,  NARITA Yoshitaka (National Cancer Center Hospital, Dep. of Neurosurgery and Neuro-Oncology, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, JPN) ,  TAKAMI Hirokazu (National Cancer Center Res. Inst., Div. of Brain Tumor Translational Res., 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, JPN) ,  TAKAMI Hirokazu (Univ. of Tokyo, Dep. of Neurosurgery, 7-3-1 Hongo, Bunkyo-ku, 113-0033, Tokyo, JPN) ,  FUKUSHIMA Shintaro (National Cancer Center Res. Inst., Div. of Brain Tumor Translational Res., 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, JPN) ,  MATSUSHITA Yuko (National Cancer Center Hospital, Dep. of Neurosurgery and Neuro-Oncology, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, JPN) ,  YOSHIDA Akihiko (National Cancer Center Hospital, Dep. of Pathology and Clinical Laboratories, Tokyo, JPN) ,  MIYAKITA Yasuji (National Cancer Center Hospital, Dep. of Neurosurgery and Neuro-Oncology, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, JPN) ,  OHNO Makoto (National Cancer Center Hospital, Dep. of Neurosurgery and Neuro-Oncology, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, JPN) ,  SHIBUI Soichiro (National Cancer Center Hospital, Dep. of Neurosurgery and Neuro-Oncology, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, JPN) ,  ICHIMURA Koichi (National Cancer Center Res. Inst., Div. of Brain Tumor Translational Res., 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, JPN)
Material： Acta Neuropathologica
Volume： 126  Issue： 6  Page： 939-941  Publication year： Dec. 2013 
JST Material Number： A0895B  ISSN： 0001-6322  CODEN： ANPTA  Document type： Article
Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Terms in the title (8)： メチル化 ,  TERT ,  プロモーター ,  変異 ,  成人 ,  神経膠腫 ,  アップレギュレーション ,  メカニズム