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J-GLOBAL ID:201302298391402659   Reference number:13A1892175

YB1 binds to and represses the p16 tumor suppressor gene

YB1は癌抑制遺伝子p16に結合してその転写を抑制する
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Material:
Volume: 18  Issue: 11  Page: 999-1006  Publication year: Nov. 2013 
JST Material Number: W0935A  ISSN: 1356-9597  CODEN: GECEFL  Document type: Article
Article type: 原著論文  Country of issue: Australia (AUS)  Language: ENGLISH (EN)
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Chemistry,biochemistry and pathology of tumors(=neoplasms)  ,  Gene expression 
Reference (37):
  • Asakuno, K., Kohno, K., Uchiumi, T., Kubo, T., Sato, S., Isono, M. & Kuwano, M. (1994) Involvement of a DNA binding protein, MDR-NF1/YB-1, in human MDR1 gene expression by actinomycin D. Biochem. Biophys. Res. Commun. 199, 1428-1435.
  • Bargou, R.C., Jurchott, K., Wagener, C., Bergmann, S., Metzner, S., Bommert, K., Mapara, M.Y., Winzer, K.J., Dietel, M., Dorken, B. & Royer, H.D. (1997) Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression. Nat. Med. 3, 447-450.
  • Basaki, Y., Taguchi, K., Izumi, H., Murakami, Y., Kubo, T., Hosoi, F., Watari, K., Nakano, K., Kawaguchi, H., Ohno, S., Kohno, K., Ono, M. & Kuwano, M. (2010) Y-box binding protein-1 (YB-1) promotes cell cycle progression through CDC6-dependent pathway in human cancer cells. Eur. J. Cancer 46, 954-965.
  • Bergmann, S., Royer-Pokora, B., Fietze, E., Jurchott, K., Hildebrandt, B., Trost, D., Leenders, F., Claude, J.C., Theuring, F., Bargou, R., Dietel, M. & Royer, H.D. (2005) YB-1 provokes breast cancer through the induction of chromosomal instability that emerges from mitotic failure and centrosome amplification. Cancer Res. 65, 4078-4087.
  • Bracken, A.P., Kleine-Kohlbrecher, D., Dietrich, N., Pasini, D., Gargiulo, G., Beekman, C., Theilgaard-Monch, K., Minucci, S., Porse, B.T., Marine, J.C., Hansen, K.H. & Helin, K. (2007) The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. Genes Dev. 21, 525-530.
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