Toda Satoshi

トダサトシ | Toda Satoshi

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://sites.google.com/view/satoshitodalab/home

Research field (4)： Morphology, anatomy , Molecular biology , Applied molecular and cellular biology , Cell biology

Research keywords (7)： Synthetic biology , Protein engineering , Cell engineering , Self-organization , Cell-cell communication , Morphogenesis , Cytoskeleton

Research theme for competitive and other funds (13)：

2021 - 2026 細胞の競合的コミュニケーションの設計による組織自律性の生成原理の解明
2023 - 2025 Development of CAR-T cell therapy for non-small cell lung cancer targeting the cancer-specific epitope associated with altered glycosylation in CD98hc protein
2021 - 2025 Exploring design principles of multicellular patterning by engineering customized cell-cell communications
2020 - 2023 細胞の形態・運動の操作を実現する人工受容体システムの開発
2020 - 2023 組織形成環境を制御するデザイナーニッチ細胞の開発

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Papers (14)：

Noyuri Zama, Satoshi Toda. Designer cell therapy for tissue regeneration. Inflammation and Regeneration. 2024
Joanne C. Lee, Hannah J. Brien, Bonnie L. Walton, Zachary M. Eidman, Satoshi Toda, Wendell A. Lim, Jonathan M. Brunger. Instructional materials that control cellular activity through synthetic Notch receptors. Biomaterials. 2023. 297. 122099-122099
Sristilekha Nath, Satoshi Toda, Satoru Okuda. Intestinal and optic-cup organoids as tools for unveiling mechanics of self-organizing morphogenesis. Biophysics and Physicobiology. 2022. 19. e190048
Satoshi Watanabe, Yuta Nihongaki, Kie Itoh, Toru Uyama, Satoshi Toda, Shigeki Watanabe, Takanari Inoue. Defunctionalizing intracellular organelles such as mitochondria and peroxisomes with engineered phospholipase A/acyltransferases. Nature Communications. 2022. 13. 1. 4413
Keisuke Kuromiya, Kana Aoki, Kojiro Ishibashi, Moe Yotabun, Miho Sekai, Nobuyuki Tanimura, Sayuri Iijima, Susumu Ishikawa, Tomoko Kamasaki, Yuki Akieda, et al. Calcium sparks enhance the tissue fluidity within epithelial layers and promote apical extrusion of transformed cells. Cell Reports. 2022. 40. 2. 111078

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MISC (9)：

Satoshi Toda. 人工受容体技術が変革するCAR-T細胞医薬のデザイン. 2023. 41. 18
戸田聡. 細胞間相互作用の再構成による多細胞構造の形成. 生体の科学. 2022. 73. 4. 333-336
水野皓介, 戸田聡. 人工モルフォゲンによる多細胞パターンのデザイン. 月刊「細胞」. 2021. 53. 10
戸田聡. 細胞分化パターンの操作を可能とする人工モルフォゲンシステムの開発. 実験医学. 2021. 39. 6
戸田聡. 人工受容体技術を用いた細胞医薬のデザイン. 実験医学増刊号. 2020. 38. 17

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Patents (1)：

Binding-triggered Transcriptional Switches and Methods of Use Thereof.

Lectures and oral presentations (53)：

Designer niche cells to engineer tissue environment
(RIKEN BDR Organoid Workshop “Exploring Organoid Design with Microengineering” 2024)
Exploring the regulatory mechanisms of Wnt signal gradient with synthetic receptor systems
(The 6th ExCELLS Symposium 2024)
Programming multicellular pattern formation with synthetic cell-cell signaling
(Cell Bio 2023 - An ASCB|EMBO Meeting 2023)
Reconstructing morphogen system to program multicellular patterning
(The 96th Annual Meeting of the Japanese Biochemical Society 2023)
細胞間コミュニケーションの操作による多細胞パターンのデザイン
(量子生命科学先端フォーラム 2023夏の研究会 2023)

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Education (3)：

2011 - 2014 Kyoto University Graduate School of Medicine
2009 - 2011 Kyoto University Graduate School of Biostudies
2005 - 2009 Kyoto University Faculty of engineering Undergraduate School of Engineering Science

Professional career (1)：

博士(医科学) (京都大学)

Work history (7)：

2024/04 - 現在 Osaka University Institute for Protein Research Associate Professor
2021/10 - 現在 PRESTO Researcher, JST
2019/10 - 2024/03 Kanazawa University Nano Life Science Institute Assistant Professor (Jr.PI)
2015/04 - 2019/09 University of California San Francisco Postdoctoral fellow
2016/04 - 2019/03 Human Frontier Science Program Long term fellow

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Awards (5)：

2022/04 - The Young Scientists’ Award, The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology
2020/09 - Iwadare Scholarship Foundation Iwadare Scholarship Foundation Award
2013/09 - The Japanese Biochemical Society Koichi Suzuki Memorial Award
2012/09 - Kyoto University Faculty of Medicine Young Investigator Award
2009/03 - The Japan Society of Mechanical Engineers Hatakeyama award

Association Membership(s) (3)：

JAPANESE SOCIETY of DEVELOPMENTAL BIOLOGISTS , The Molecular Biology Society of Japan , THE JAPANESE BIOCHEMICAL SOCIETY

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