Research theme for competitive and other funds (5)：
2022 - 2025 Study on the spatio-temporal dynamics of calcium and glutamate coupling at sensory ribbon synapses.
2021 - 2024 Elucidation of Ca sparks in CNS presynaptic terminals
2017 - 2020 シナプスの短期可塑性を制御する即時放出可能シナプス小胞の空間分布の解明
2011 - 2012 Developmental changes in Ca channel density and single channel conductance at the presynaptic terminal of central nervous system
2008 - 2010 Developmental changes in calcium domain at the presynaptic terminal of the central synapse
Papers (17)：
Mitsuharu Midorikawa, Hirokazu Sakamoto, Yukihiro Nakamura, Kenzo Hirose, Mariko Miyata. Developmental refinement of the active zone nanotopography and axon wiring at the somatosensory thalamus. Cell Reports. 2024
Peter Koppensteiner, Pradeep Bhandari, Cihan Önal, Carolina Borges-Merjane, Elodie Le Monnier, Utsa Roy, Yukihiro Nakamura, Tetsushi Sadakata, Makoto Sanbo, Masumi Hirabayashi, et al. GABA B receptors induce phasic release from medial habenula terminals through activity-dependent recruitment of release-ready vesicles. Proceedings of the National Academy of Sciences. 2024
Patch-clamp recording method in slices for studying presynaptic mechanisms
2012
最新パッチクランプ実験技術法
吉岡書店 2011 ISBN:9784842703589
Lectures and oral presentations (24)：
EGTA can inhibit vesicular release in the 'nanodomain' distance from Ca channels
(IBRO2019 2019)
Ca2+ gradients at the vicinity of the Ca2+ channel: a comparison between linearized buffer approximation and reaction-diffusion simulation
(The 41st Annual Meeting of the Japan Neuroscience Society 2018)
The estimate of spatial distribution of readily-releasable vesicles at a central presynaptic terminal
(The 95th Annual Meeting of the Physiological Society Meeting 2018)
Inhibition of nanodomain Ca-driven vesicular release by EGTA
(The 40th Annual Meeting of the Japan Neuroscience Society 2017)
