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J-GLOBAL ID：201402200212191834   Reference number：14A1452375

Competitive regulation of human intestinal β-carotene 15,15′-monooxygenase 1 (BCMO1) gene expression by hepatocyte nuclear factor (HNF)-1α and HNF-4α

肝細胞細胞核因子(HNF)-1αおよびHNF-4αによるヒト腸β-カロテン15,15′-モノオキシゲナーゼ(BCMO1)遺伝子発現の拮抗調節

Author (4)： YAMAGUCHI Noriaki (Lab. of Nutritional Physiology, Graduate School of Human Health Sciences, Univ. of Nagasaki Siebold, Nagasaki ...) ,  SUNTO Akiko (Lab. of Nutritional Physiology, Graduate School of Nutritional and Environmental Sciences and Global COE, Univ. of ...) ,  GODA Toshinao (Lab. of Nutritional Physiology, Graduate School of Nutritional and Environmental Sciences and Global COE, Univ. of ...) ,  SURUGA Kazuhito (Lab. of Nutritional Physiology, Graduate School of Human Health Sciences, Univ. of Nagasaki Siebold, Nagasaki ...)
Material： Life Sciences  (Life Sciences including Pharmacology Letters)
Volume： 119  Issue： 1-2  Page： 34-39  Publication year： Dec. 05, 2014 
JST Material Number： B0699B  ISSN： 0024-3205  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： DNA binding protein ,  nuclear protein ,  transcription factor ,  *fatty acid desaturase ,  gene ,  *genetic regulation ,  *vitamin A ,  Caco2 cell ,  immunoprecipitation ,  gel electrophoresis ,  promoter(genetics) ,  RT-PCR ,  bioassay ,  emission spectrometry ,  *gene expression ,  carotenoid
Semi thesaurus term： HNF-1 alpha ,  HNF-4 alpha ,  *beta-Carotene 15,15'-Monooxygenase ,  enzyme gene ,  *Gene Expression Regulation ,  BCMO1遺伝子 ,  Chromatin Immunoprecipitation ,  electrophoretic mobility shift assay ,  Real-time RT-PCR ,  luciferase assay

JST classification (3)： Basic medicine on digestive system  (GH01020E) ,  Enzyme in general  (EB09010D) ,  Gene expression  (EC02040Q)

Substance index (1)： β-Carotine

Terms in the title (12)： 肝細胞 ,  細胞核 ,  因子 ,  HNF ,  HNF-4α ,  ヒト ,  腸 ,  β-カロテン ,  モノオキシゲナーゼ ,  遺伝子発現 ,  拮抗 ,  調節