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J-GLOBAL ID：201402204504011662   Reference number：14A1213885

Seasonal Difference in Percutaneous Absorption of N,N-Dimethylformamide as Determined Using Two Urinary Metabolites

2種の尿中代謝産物を用いて測定したN,N-ジメチルホルムアミドの経皮吸収の季節の違い

Author (7)： TSUDA Yoko (Dep. of Preventive Medicine and Public Health, Shinshu Univ. School of Medicine) ,  MIYAUCHI Hiroyuki (Assoc. of Industrial Health) ,  MINOZOE Aoi (Assoc. of Industrial Health) ,  TANAKA Shigeru (Dep. of Public Health, Graduate School of Human Life Sci., Jumonji Univ.) ,  ARITO Heihachiro (Occupational Health Res. and Dev. Center, Japan Industrial Safety and Health Assoc.) ,  TSUKAHARA Teruomi (Dep. of Preventive Medicine and Public Health, Shinshu Univ. School of Medicine) ,  NOMIYAMA Tetsuo (Dep. of Preventive Medicine and Public Health, Shinshu Univ. School of Medicine)
Material： Journal of Occupational Health  (J Occup Health)
Volume： 56  Issue： 4  Page： 252-259 (J-STAGE)  Publication year： 2014 
JST Material Number： L2813A  ISSN： 1341-9145  CODEN： JOCHFV  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *organic solvent ,...
Semi thesaurus term： pollution monitoring ,...

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JST classification (3)： Occupational health,industorial accidents  (GB05000S) ,  Metabolism and biotransformasion of xenobiotics  (EJ02037P) ,  Examination and measurement of harmful gas  (SB03050T)

Substance index (3)： Dimethylformamide ,  N-Methylformamide ,  AMCC

Reference (35)：

• 1) Trochimowicz HJ, Kennedy Jr GL, Krivanek ND. Dimethylformamide. In: Bingham E, Cohrssen B, Powell CH, editors. Patty's Toxicology. 5th Ed Vol. 4. New York: John Wiley & Sons, Inc.; 2001. p. 1318-26.
• 2) N,N,-Dimethylformamide. In: Chemical Products Handbook-16313. Tokyo: The Chemical Daily Co.; 2013. p. 537-8. (in Japanese)
• 3) Potter HP. Dimethyformamide-induced abdominal pain and liver injury. Arch Environ Health 1973; 27: 340-1.
• 4) He J, Wang P, Zhu J-Q, Wu G, Ji J-M, Xue Y. Role of urinary biomarkers of N,N-dimethylformamide in the early detection of hepatic injury among occupational exposed workers. Int Arch Occup Environ Health 2010; 83: 399-406.
• 5) Nomiyama T, Uehara M, Miyauchi H, Imamiya S, Tanaka S, Seki Y. Causal relationship between a case of severe hepatic dysfunction and low exposure concentrations of N,N-dimethylformamide in the synthetic industry. Ind Health 2001; 39: 33-6.

Terms in the title (4)： 尿中代謝産物 ,  ジメチルホルムアミド ,  経皮吸収 ,  季節