Art

J-GLOBAL ID：201402208358163477   Reference number：14A0221409

縮環系骨格の構築法を基にした天然物の合成

Author (2)： SUZUKI TAKAHIRO (東京理大 薬) ,  SUZUKI TAKAHIRO (早稲田大 理工学術院 先進理工)
Material： 上原記念生命科学財団研究報告集(CD-ROM)
Volume： 27  Page： ROMBUNNO.18  Publication year： Dec. 10, 2013 
JST Material Number： J1247B  ISSN： 2433-3441  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *chemical synthesis ,...
Semi thesaurus term： aconitum alkaloid ,...

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JST classification (4)： Synthesis of drugs  (GV01030F) ,  Basic research of antiviral drugs  (GW17040O) ,  Basic research of antibacterial drugs  (GW17020S) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (4)： Chloropupukeananin ,  Bicyclo(2.2.2)octane ,  o-Benzoquinone ,  (2S)-2,10-[(R)-1-Hydroxy-2-propene-1,2-diyl]-1,3-propano-2β,4aβ-ethylene-5β-methyl-5-formyl-1,2,3,4,4a,5,6,7-octahydronaphthalene-4-one

Reference (5)：

• Liu, L., Liu, S. C., Jiang, L. H., Chen, X. L., Guo, L. D. & Che, Y. S. : Chloropupukeananin, the first chlorinated pupukeanane derivative, and its precursors from Pestalotiopsis fici. Org. Lett., 10 : 1397-1400, 2008.
• Suzuki, T. & Kobayashi, S. : Concise approach to pupukeanane skeleton: synthetic study of chloropupukeananin. Org. Lett., 12 : 2920-2923, 2010.
• Suzuki, T., Miyajima, Y., Suzuki, K., Iwakiri, K., Koshimizu, M., Hirai, G., Sodeoka, M. & Kobayashi, S. : Unexpected Diels-Alder/carbonyl-ene cascade toward the biomimetic synthesis of chloropupukeananin. Org. Lett., 15 : 1748-1751, 2013.
• Tang, P., Chen, Q.-H. & Wang, F.-P. : Atropurpuran, a novel diterpene with an unprecedented pentacyclic cage skeleton, from Aconitum hemsleyanum var. atropurpureum. Tetrahedron Lett., 50 : 460-462, 2009.
• Suzuki, T., Sasaki, A., Egashira, N. & Kobayashi, S. : A synthetic study of atropurpuran: construction of a pentacyclic framework by an intramolecular reverse-electron-demand Diels-Alder reaction. Angew. Chem. Int. Ed. Engl., 50 : 9177-9179, 2011.

Terms in the title (4)： 環 ,  骨格 ,  構築 ,  天然物