Art

J-GLOBAL ID：201402211051518473   Reference number：14A1154511

Evaluation of radical scavenging properties of shikonin

シコニンのラジカルスカベンジャー特性の評価

Author (7)： YOSHIDA Lucia S. (Res. Inst. of Pharmaceutical Sciences, Musashino Univ.) ,  KOHRI Shunji (Center for Medical Education, Sapporo Medical Univ.) ,  TSUNAWAKI Shohko (Dep. of Biochemistry, Showa Univ. School of Medicine) ,  KAKEGAWA Tomohito (Fac. of Pharmaceutical Sciences, Josai International Univ.) ,  TANIGUCHI Taizo (Fac. of Pharmaceutical Sciences, Himeji Dokkyo Univ.) ,  TAKANO-OHMURO Hiromi (Res. Inst. of Pharmaceutical Sciences, Musashino Univ.) ,  FUJII Hirotada (Center for Medical Education, Sapporo Medical Univ.)
Material： Journal of Clinical Biochemistry and Nutrition  (JCBN)
Volume： 55  Issue： 2  Page： 90-96 (J-STAGE)  Publication year： 2014 
JST Material Number： X0851A  ISSN： 0912-0009  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *scavenger ,...
Semi thesaurus term： naphthoquinone ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=14A1154511&from=J-GLOBAL&jstjournalNo=X0851A") }}

JST classification (2)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Biophylaxis and immune systems in general  (ED01010F)

Substance index (2)： Shikonin ,  Trolox

Reference (43)：

• 1 Papageorgiou VP, Assimopoulou AN, Couladouros EA, Hepworth D, Nicolaou KC. The chemistry and biology of alkannin, shikonin and related naphthazarin natural products. Angew Chem Int Ed 1999; 38: 270-301.
• 2 Chen X, Yang L, Oppenheim JJ, Howard MZ. Cellular pharmacology studies of shikonin derivatives. Phytother Res 2002; 16: 199-209.
• 3 Papageorgiou VP, Assimopoulou AN, Ballis AC. Alkannins and shikonins: a new class of wound healing agents. Curr Med Chem 2008; 15: 3248-3267.
• 4 Takano-Ohmuro H, Yoshida LS, Yuda Y, Morioka K, Kitani S. Shikonin inhibits IgE-mediated histamine release by human basophils and Syk kinase activity. Inflamm Res 2008; 57: 484-488.
• 5 Yoshida LS, Kawada T, Irie K, et al. Shikonin directly inhibits nitric oxide synthases: possible targets that affect thoracic aorta relaxation response and nitric oxide release from RAW 264.7 macrophages. J Pharmacol Sci 2010; 112: 343-351.

Terms in the title (3)： シコニン ,  ラジカルスカベンジャー ,  評価