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J-GLOBAL ID：201402225653009201   Reference number：14A1353674

Effects of N-[N-(3, 5-difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester (DAPT) on cell proliferation and apoptosis in Ishikawa endometrial cancer cells

N-[N-(3,5-ジフルオロフェナセチル-L-アラニル)]-S-フェニルグリシンt-ブチルエステル(DAPT)がIshikawa子宮内膜癌細胞の細胞増殖とアポトーシスに及ぼす作用

Author (16)： MORI Michihiro (Kurashiki Univ. Sci. and the Arts, Okayama, JPN) ,  MIYAMOTO Tomoyuki (Kurashiki Univ. Sci. and the Arts, Okayama, JPN) ,  MIYAMOTO Tomoyuki (Kake Inst. of Cytopathology, Okayama, JPN) ,  YAKUSHIJI Hiromasa (Kurashiki Univ. Sci. and the Arts, Okayama, JPN) ,  OHNO Setsuyo (Kurashiki Univ. Sci. and the Arts, Okayama, JPN) ,  OHNO Setsuyo (Kake Inst. of Cytopathology, Okayama, JPN) ,  MIYAKE Yasuyuki (Kurashiki Univ. Sci. and the Arts, Okayama, JPN) ,  MIYAKE Yasuyuki (Kake Inst. of Cytopathology, Okayama, JPN) ,  SAKAGUCHI Takuya (Kurashiki Univ. Sci. and the Arts, Okayama, JPN) ,  SAKAGUCHI Takuya (Kake Inst. of Cytopathology, Okayama, JPN) ,  HATTORI Manabu (Kitasato Univ., Kanagawa, JPN) ,  HONGO Atsushi (Okayama Univ. Graduate School of Medicine, Dentistry and Pharmaceutical Sci., Okayama, JPN) ,  NAKAIZUMI Akihiko (Kyoto Univ., Kyoto, JPN) ,  UEDA Masatsugu (Osaka Cancer Prevention and Detection Center, Osaka, JPN) ,  OHNO Eiji (Kurashiki Univ. Sci. and the Arts, Okayama, JPN) ,  OHNO Eiji (Kake Inst. of Cytopathology, Okayama, JPN)
Material： Human Cell (Web)  (Hum Cell (Web))
Volume： 25  Issue： 1  Page： 9-15 (WEB ONLY)  Publication year： Mar. 2012 
JST Material Number： U0492A  ISSN： 1749-0774  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *endometrial carcinoma ,...
Semi thesaurus term： *gamma-secretase inhibitor ,...

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JST classification (3)： Tumors(=neoplasms)of female genitalia and fetus  (GS04000K) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Cell physiology in general  (EF02010S)

Substance index (1)： DAPT

Reference (24)：

• Okuda T, Sekizawa A, Purwosunu Y, et al. Genetics of endometrial cancers. Obstet Gynecol Int. 2010;2010:984013.
• Masciullo V, Amadio G, Lo Russo D, Raimondo I, Giordano A, Scambia G. Controversies in the management of endometrial cancer. Obstet Gynecol Int. 2010;2010:638165.
• Bakkum-Gamez JN, Gonzalez-Bosquet J, Laack NN, Mariani A, Dowdy SC. Current issues in the management of endometrial cancer. Mayo Clin Proc. 2008;83:97-112.
• Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science. 1999;284:770-6.
• Wilson A, Radtke F. Multiple functions of Notch signaling in self-renewing organs and cancer. FEBS Lett. 2006;580:2860-8.

Terms in the title (6)： フェニルグリシン ,  DAPT ,  子宮内膜 ,  癌細胞 ,  細胞増殖 ,  アポトーシス