Rat hepatocyte spheroids formed on temperature-responsive PIPAAm polymer-grafted surface maintain long-term differentiated hepatocyte function

TOMONAGA Tetsuo; SOYAMA Akihiko; YAMANOUCHI Kosho; TAKATSUKI Mitsuhisa; KUROKI Tamotsu; KOJI Takehiko; EGUCHI Susumu

Art

J-GLOBAL ID：201402225985861335 Reference number：14A1145294

Rat hepatocyte spheroids formed on temperature-responsive PIPAAm polymer-grafted surface maintain long-term differentiated hepatocyte function

温度応答性PIPAAmポリマーグラフト表面に形成されるラット肝細胞スフェロイドは長期分化型肝細胞機能を保持する

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Material：
Volume： 59 Issue： 1 Page： 1-6 Publication year： Jul. 2014
JST Material Number： X0952A ISSN： 0001-6055 Document type： Article
Article type：原著論文 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Basic medicine on digestive system , Cell and tissue culture methods , Liver , Cell physiology in general

Reference (18)：

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Yamada N, Okano T, Sakai H, et al. Thermo-responsive polymeric surfaces; control of attachment and detachment of cultured cells. Makromol. Chem., Rapid Commun. 11: 571-576, 1990
Okano T, Yamada N, Sakai H, et al. A novel recovery system for cultured cells using plasma-treated polystyrene dishes grafted with poly(N-isopropylacrylamide). J. Biomed Mater Res. 27: 1243-1251, 1993
Nishida K, Yamato M, Hayashida Y, et al. Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium. N Engl J Med. 351: 1187-1196, 2004

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