Art

J-GLOBAL ID：201402258577459672   Reference number：14A0393189

Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3

ブドウ糖は細胞表面のブドウ糖感知受容体T1R3に作用することにより,自分自身の代謝を促進する

Author (5)： NAKAGAWA Yuko (Inst. for Molecular & Cellular Regulation, Gunma Univ., Maebashi 371-8512, JPN) ,  OHTSU Yoshiaki (Inst. for Molecular & Cellular Regulation, Gunma Univ., Maebashi 371-8512, JPN) ,  NAGASAWA Masahiro (Inst. for Molecular & Cellular Regulation, Gunma Univ., Maebashi 371-8512, JPN) ,  SHIBATA Hiroshi (Inst. for Molecular & Cellular Regulation, Gunma Univ., Maebashi 371-8512, JPN) ,  KOJIMA Itaru (Inst. for Molecular & Cellular Regulation, Gunma Univ., Maebashi 371-8512, JPN)
Material： Endocrine Journal  (Endocr J)
Volume： 61  Issue： 2  Page： 119-131 (J-STAGE)  Publication year： 2014 
JST Material Number： F0625A  ISSN： 0918-8959  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： dosage dependence

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=14A0393189&from=J-GLOBAL&jstjournalNo=F0625A") }}

JST classification (4)： Basic medicine on endocrine system  (GL01020Q) ,  Basic medicine on digestive system  (GH01020E) ,  Pancreas  (EJ06050Y) ,  Metabolism in general  (EB06030E)

Substance index (4)： Glucose ,  adenosine triphosphate ,  Sucralose ,  3-O-Methylglucose

Reference (22)：

• 1. Rorsman P (1997) The pancreatic β-cell as a fuel sensor. Diabetologia 40: 487-495.
• 2. Henquin JC (2009) Regulation of insulin secretion: a matter of phase control and amplitude modulation. Diabetologia 52: 739-751.
• 3. Komatsu M, Sato Y, Aizawa T, Hashizume K (2001) K_ATP channel-independent glucose action: an elusive pathway in stimulus-secretion coupling of pancreatic β-cells. Endocr J 48: 275-288.
• 4. Nakagawa Y, Nagasawa M, Yamada S, Hara A, Mogami H, et al. (2009) Sweet taste receptor expressed in pancreatic β-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion. PLoS One 4: e5106.
• 5. Temussi P (2007) The sweet taste receptor: a single receptor with multiple sites and model of interaction. Adv Food Nutr Res 53: 199-239.

Terms in the title (8)： ブドウ糖 ,  細胞表面 ,  感知 ,  受容体 ,  T1R3 ,  自身 ,  代謝 ,  促進