Art

J-GLOBAL ID：201402258577459672   Reference number：14A0393189

Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3

ブドウ糖は細胞表面のブドウ糖感知受容体T1R3に作用することにより,自分自身の代謝を促進する

Author (5)： NAKAGAWA Yuko (Inst. for Molecular & Cellular Regulation, Gunma Univ., Maebashi 371-8512, JPN) ,  OHTSU Yoshiaki (Inst. for Molecular & Cellular Regulation, Gunma Univ., Maebashi 371-8512, JPN) ,  NAGASAWA Masahiro (Inst. for Molecular & Cellular Regulation, Gunma Univ., Maebashi 371-8512, JPN) ,  SHIBATA Hiroshi (Inst. for Molecular & Cellular Regulation, Gunma Univ., Maebashi 371-8512, JPN) ,  KOJIMA Itaru (Inst. for Molecular & Cellular Regulation, Gunma Univ., Maebashi 371-8512, JPN)
Material： Endocrine Journal  (Endocr J)
Volume： 61  Issue： 2  Page： 119-131 (J-STAGE)  Publication year： 2014 
JST Material Number： F0625A  ISSN： 0918-8959  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *T1R3 ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=14A0393189&from=J-GLOBAL&jstjournalNo=F0625A") }}

JST classification (4)： Basic medicine on endocrine system  (GL01020Q) ,  Basic medicine on digestive system  (GH01020E) ,  Pancreas  (EJ06050Y) ,  Metabolism in general  (EB06030E)

Substance index (4)： Glucose ,  adenosine triphosphate ,  Sucralose ,  3-O-Methylglucose

Reference (22)：

• 1. Rorsman P (1997) The pancreatic β-cell as a fuel sensor. Diabetologia 40: 487-495.
• 2. Henquin JC (2009) Regulation of insulin secretion: a matter of phase control and amplitude modulation. Diabetologia 52: 739-751.
• 3. Komatsu M, Sato Y, Aizawa T, Hashizume K (2001) K_ATP channel-independent glucose action: an elusive pathway in stimulus-secretion coupling of pancreatic β-cells. Endocr J 48: 275-288.
• 4. Nakagawa Y, Nagasawa M, Yamada S, Hara A, Mogami H, et al. (2009) Sweet taste receptor expressed in pancreatic β-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion. PLoS One 4: e5106.
• 5. Temussi P (2007) The sweet taste receptor: a single receptor with multiple sites and model of interaction. Adv Food Nutr Res 53: 199-239.

Terms in the title (8)： ブドウ糖 ,  細胞表面 ,  感知 ,  受容体 ,  T1R3 ,  自身 ,  代謝 ,  促進