Art

J-GLOBAL ID：201402260424914073   Reference number：14A0774755

Meta-analysis of the Risk of Upper Gastrointestinal Hemorrhage with Combination Therapy of Selective Serotonin Reuptake Inhibitors and Non-steroidal Anti-inflammatory Drugs

選択的セロトニン再取り込み阻害薬と非ステロイド性抗炎症薬の併用療法に伴う上部消化管出血のリスクのメタアナリシス

Author (8)： OKA Yoshinari (School of Pharmaceutical Sciences, Osaka Univ.) ,  OKA Yoshinari (Pharmacy Dep., Osaka City Sumiyoshi Hospital) ,  OKAMOTO Kousuke (Graduate School of Pharmaceutical Sciences, Osaka Univ.) ,  KAWASHITA Norihito (Graduate School of Pharmaceutical Sciences, Osaka Univ.) ,  KAWASHITA Norihito (Inst. for Microbial Diseases, Osaka Univ.) ,  SHIRAKUNI Yuko (Graduate School of Pharmaceutical Sciences, Osaka Univ.) ,  TAKAGI Tatsuya (Graduate School of Pharmaceutical Sciences, Osaka Univ.) ,  TAKAGI Tatsuya (Inst. for Microbial Diseases, Osaka Univ.)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 37  Issue： 6  Page： 947-953 (J-STAGE)  Publication year： 2014 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *UGI bleed

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JST classification (2)： Clinical application of anti-inflammatory drugs  (GW15020E) ,  Clinical application of other drugs acting on central nervous system  (GW03130F)

Reference (19)：

• 1) Dalton SO, Johansen C, Mellemkjær L, Nørgård B, Sørensen HT, Olsen JH. Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal tract bleeding: a population-based cohort study. Arch. Intern. Med., 163, 59-64 (2003).
• 2) Targownik LE, Bolton JM, Metge CJ, Leung S, Sareen J. Selective serotonin reuptake inhibitors are associated with a modest increase in the risk of upper gastrointestinal bleeding. Am. J. Gastroenterol., 104, 1475-1482 (2009).
• 3) Loke YK, Trivedi AN, Singh S. Meta-analysis: gastrointestinal bleeding due to interaction between selective serotonin uptake inhibitors and non-steroidal anti-inflammatory drugs. Aliment. Pharmacol. Ther., 27, 31-40 (2008).
• 4) Gasse C, Christensen S, Riis A, Mortensen PB, Adamsen S, Thomsen RW. Preadmission use of SSRIs alone or in combination with NSAIDs and 30-day mortality after peptic ulcer bleeding. Scand. J. Gastroenterol., 44, 1288-1295 (2009).
• 5) Macaskill P, Walter SD, Irwig L. A comparison of methods to detect publication bias in meta-analysis. Stat. Med., 20, 641-654 (2001).

Terms in the title (6)： 選択的セロトニン再取り込み阻害薬 ,  非ステロイド性抗炎症薬 ,  併用療法 ,  上部消化管出血 ,  リスク ,  メタアナリシス